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Trends in colorectal cancer mortality in hispanics: a SEER analysis

BACKGROUND: Colorectal cancer (CRC) mortality among Hispanics is lower than Non-Hispanic Whites (NHW). If Hispanics receive equitable care and achieve the same degree of health benefit, their trend of better survival should be maintained. This study assesses mortality trends among Hispanics overtime...

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Autores principales: Barzi, Afsaneh, Yang, Dongyun, Mostofizadeh, Sayedamin, Lenz, Heinz-Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752479/
https://www.ncbi.nlm.nih.gov/pubmed/29312566
http://dx.doi.org/10.18632/oncotarget.21938
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author Barzi, Afsaneh
Yang, Dongyun
Mostofizadeh, Sayedamin
Lenz, Heinz-Josef
author_facet Barzi, Afsaneh
Yang, Dongyun
Mostofizadeh, Sayedamin
Lenz, Heinz-Josef
author_sort Barzi, Afsaneh
collection PubMed
description BACKGROUND: Colorectal cancer (CRC) mortality among Hispanics is lower than Non-Hispanic Whites (NHW). If Hispanics receive equitable care and achieve the same degree of health benefit, their trend of better survival should be maintained. This study assesses mortality trends among Hispanics overtime to compare their survival improvement with NHW. METHODS: We used the Incidence-Based Mortality database of the Surveillance, Epidemiology, and End Results Program (SEER) to assess the mortality gap, which is defined as the difference in stage-specific mortality between NHWs and Hispanics, and currently has an advantage for Hispanics. RESULTS: There is a statistically significant disparity in stage-specific mortality of CRC by race, with a higher proportion of deaths from metastatic disease among Hispanics than NHW (48% vs. 44% respectively). Comparing the time intervals of 2000-2005 and 2006-2011, mortality was reduced by 15.1% for NHWs and 5.9% for Hispanics, resulting in a narrowing of the mortality gap. The mortality gap between Hispanics and NHW is tapering overtime for every stage of the disease, reflecting that Hispanics have a disparity in CRC mortality. CONCLUSION: The mortality gap between Hispanics and NHWs is narrowing, supporting a significantly lower rate of mortality improvement in Hispanics. If the current trend continues, mortality rates in Hispanics will outpace that of NHWs.
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spelling pubmed-57524792018-01-08 Trends in colorectal cancer mortality in hispanics: a SEER analysis Barzi, Afsaneh Yang, Dongyun Mostofizadeh, Sayedamin Lenz, Heinz-Josef Oncotarget Research Paper BACKGROUND: Colorectal cancer (CRC) mortality among Hispanics is lower than Non-Hispanic Whites (NHW). If Hispanics receive equitable care and achieve the same degree of health benefit, their trend of better survival should be maintained. This study assesses mortality trends among Hispanics overtime to compare their survival improvement with NHW. METHODS: We used the Incidence-Based Mortality database of the Surveillance, Epidemiology, and End Results Program (SEER) to assess the mortality gap, which is defined as the difference in stage-specific mortality between NHWs and Hispanics, and currently has an advantage for Hispanics. RESULTS: There is a statistically significant disparity in stage-specific mortality of CRC by race, with a higher proportion of deaths from metastatic disease among Hispanics than NHW (48% vs. 44% respectively). Comparing the time intervals of 2000-2005 and 2006-2011, mortality was reduced by 15.1% for NHWs and 5.9% for Hispanics, resulting in a narrowing of the mortality gap. The mortality gap between Hispanics and NHW is tapering overtime for every stage of the disease, reflecting that Hispanics have a disparity in CRC mortality. CONCLUSION: The mortality gap between Hispanics and NHWs is narrowing, supporting a significantly lower rate of mortality improvement in Hispanics. If the current trend continues, mortality rates in Hispanics will outpace that of NHWs. Impact Journals LLC 2017-10-19 /pmc/articles/PMC5752479/ /pubmed/29312566 http://dx.doi.org/10.18632/oncotarget.21938 Text en Copyright: © 2017 Barzi et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Barzi, Afsaneh
Yang, Dongyun
Mostofizadeh, Sayedamin
Lenz, Heinz-Josef
Trends in colorectal cancer mortality in hispanics: a SEER analysis
title Trends in colorectal cancer mortality in hispanics: a SEER analysis
title_full Trends in colorectal cancer mortality in hispanics: a SEER analysis
title_fullStr Trends in colorectal cancer mortality in hispanics: a SEER analysis
title_full_unstemmed Trends in colorectal cancer mortality in hispanics: a SEER analysis
title_short Trends in colorectal cancer mortality in hispanics: a SEER analysis
title_sort trends in colorectal cancer mortality in hispanics: a seer analysis
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752479/
https://www.ncbi.nlm.nih.gov/pubmed/29312566
http://dx.doi.org/10.18632/oncotarget.21938
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