Metformin improves nonalcoholic fatty liver disease in obese mice via down-regulation of apolipoprotein A5 as part of the AMPK/LXRα signaling pathway

Apolipoprotein A5 (apoA5) has been implicated in the formation of hepatocyte lipid droplets, a histological hallmark of non-alcoholic fatty liver disease (NAFLD). Recent evidence demonstrated that liver X receptor α (LXRα), a transcription factor involved in down-regulation of APOA5 mRNA, is activat...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Min-Jie, Dai, Wen, Scott, Melanie J., Li, Rong, Zhang, Yi-Qi, Yang, Yang, Chen, Lu-Zhu, Huang, Xian-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752482/
https://www.ncbi.nlm.nih.gov/pubmed/29312569
http://dx.doi.org/10.18632/oncotarget.22163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752482/
https://www.ncbi.nlm.nih.gov/pubmed/29312569
http://dx.doi.org/10.18632/oncotarget.22163

Ejemplares similares