Cargando…

Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients

PURPOSE: We aimed to study the potential influence of tumour blood flow –obtained from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)- in the metabolomic profiles of endometrial tumours. METHODS: Liquid chromatography coupled to mass spectrometry established the metabolomic profile o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eritja, Núria, Jové, Mariona, Fasmer, Kristine Eldevik, Gatius, Sònia, Portero-Otin, Manuel, Trovik, Jone, Krakstad, Camilla, Sol, Joaquim, Pamplona, Reinald, Haldorsen, Ingfrid S., Matias-Guiu, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752500/ https://www.ncbi.nlm.nih.gov/pubmed/29312587 http://dx.doi.org/10.18632/oncotarget.22558

Ejemplares similares

Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism
por: Jové, Mariona, et al.
Publicado: (2016)

Plasma growth differentiation factor-15 is an independent marker for aggressive disease in endometrial cancer
por: Engerud, Hilde, et al.
Publicado: (2019)

A prospective pilot study using metabolomics discloses specific fatty acid, catecholamine and tryptophan metabolic pathways as possible predictors for a negative outcome after severe trauma
por: Servià, Luis, et al.
Publicado: (2019)

Ether Lipid-Mediated Antioxidant Defense in Alzheimer’s Disease
por: Jové, Mariona, et al.
Publicado: (2023)

Lipid Adaptations against Oxidative Challenge in the Healthy Adult Human Brain
por: Jové, Mariona, et al.
Publicado: (2023)

Preoperative 18F-FDG PET/CT tumor markers outperform MRI-based markers for the prediction of lymph node metastases in primary endometrial cancer
por: Fasmer, Kristine E., et al.
Publicado: (2020)

Non-Enzymatic Modification of Aminophospholipids by Carbonyl-Amine Reactions
por: Naudí, Alba, et al.
Publicado: (2013)

Membrane lipid unsaturation as physiological adaptation to animal longevity
por: Naudí, Alba, et al.
Publicado: (2013)

Whole‐Volume Tumor MRI Radiomics for Prognostic Modeling in Endometrial Cancer
por: Fasmer, Kristine E., et al.
Publicado: (2020)

An MRI-Based Radiomic Prognostic Index Predicts Poor Outcome and Specific Genetic Alterations in Endometrial Cancer
por: Jacob, Havjin, et al.
Publicado: (2021)

The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer’s Disease Pathology
por: Jové, Mariona, et al.
Publicado: (2021)

Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice
por: Jové, Mariona, et al.
Publicado: (2014)

Metabolomic Analysis Points to Bioactive Lipid Species and Acireductone Dioxygenase 1 (ADI1) as Potential Therapeutic Targets in Poor Prognosis Endometrial Cancer
por: Gatius, Sònia, et al.
Publicado: (2022)

Antioxidants Halt Axonal Degeneration in a Mouse Model of X-Adrenoleukodystrophy
por: López-Erauskin, Jone, et al.
Publicado: (2011)

MRI-assessed tumor-free distance to serosa predicts deep myometrial invasion and poor outcome in endometrial cancer
por: Dybvik, Julie Andrea, et al.
Publicado: (2022)

Plasma long-chain free fatty acids predict mammalian longevity
por: Jové, Mariona, et al.
Publicado: (2013)

Selective brain regional changes in lipid profile with human aging
por: Mota-Martorell, Natalia, et al.
Publicado: (2022)

Blood Metabolites Associate with Prognosis in Endometrial Cancer
por: Strand, Elin, et al.
Publicado: (2019)

Plasma antioxidant capacity in critical polytraumatized patients?: methods, severity, and anatomic location
por: Serviá, Luis, et al.
Publicado: (2014)

Imaging of Preclinical Endometrial Cancer Models for Monitoring Tumor Progression and Response to Targeted Therapy
por: Espedal, Heidi, et al.
Publicado: (2019)

Preoperative pelvic MRI and 2-[(18)F]FDG PET/CT for lymph node staging and prognostication in endometrial cancer—time to revisit current imaging guidelines?
por: Fasmer, Kristine E., et al.
Publicado: (2022)

Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease
por: Lien, Hilde E., et al.
Publicado: (2023)

Corrigendum to “Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease” [EBioMedicine 92 (2023) 104595]
por: Lien, Hilde E., et al.
Publicado: (2023)

Lipidomic Alterations in the Cerebral Cortex and White Matter in Sporadic Alzheimer’s Disease
por: Obis, Elia, et al.
Publicado: (2023)

Cellular Dysfunction in Diabetes as Maladaptive Response to Mitochondrial Oxidative Stress
por: Naudi, Alba, et al.
Publicado: (2012)

Cell senescence, loss of splicing, and lipid metabolism in TDP-43-related neurodegenerative processes
por: Torres, Pascual, et al.
Publicado: (2023)

Interobserver agreement and prognostic impact for MRI–based 2018 FIGO staging parameters in uterine cervical cancer
por: Wagner-Larsen, Kari S., et al.
Publicado: (2022)

Changes in Plasma Neutral and Ether-Linked Lipids Are Associated with The Pathology and Progression of Alzheimer’s Disease
por: Dakterzada, Farida, et al.
Publicado: (2023)

When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts
por: Jové, Mariona, et al.
Publicado: (2010)

Differential metabolic profiles associated to movement behaviour of stream-resident brown trout (Salmo trutta)
por: Oromi, Neus, et al.
Publicado: (2017)

Feasibility and utility of MRI and dynamic (18)F-FDG-PET in an orthotopic organoid-based patient-derived mouse model of endometrial cancer
por: Espedal, Heidi, et al.
Publicado: (2021)

Lipid alterations in human frontal cortex in ALS‐FTLD‐TDP43 proteinopathy spectrum are partly related to peroxisome impairment
por: Andrés‐Benito, Pol, et al.
Publicado: (2021)

Development of prediction models for lymph node metastasis in endometrioid endometrial carcinoma
por: Berg, Hege F., et al.
Publicado: (2020)

Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome
por: Jové, Mariona, et al.
Publicado: (2017)

mTOR Complex 1 Content and Regulation Is Adapted to Animal Longevity
por: Mota-Martorell, Natalia, et al.
Publicado: (2022)

What MRI-based tumor size measurement is best for predicting long-term survival in uterine cervical cancer?
por: Lura, Njål, et al.
Publicado: (2022)

Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age
por: Jové, Mariona, et al.
Publicado: (2021)

Location-dependent effects of trauma on oxidative stress in humans
por: Servia, Luis, et al.
Publicado: (2018)

Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression
por: Sol, Joaquim, et al.
Publicado: (2021)

The Lipidome Fingerprint of Longevity
por: Jové, Mariona, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tgtruge53jhm0b1vndal4bvoq0