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Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib
Lung cancer is one of the deadliest malignant tumors with limited treatment options. Although targeted therapy, using tyrosine-kinase inhibitors such as erlotinib (Erlo), has shown therapeutic benefit, only 15 % patients with mutated epidermal growth factor receptor (EGFR) in lung cancer cells are s...
Autores principales: | Wang, Xiaofei, Chen, Keqiang, Yu, Ying, Xiang, Yi, Kim, Jae Hong, Gong, Wanghua, Huang, Jiaqiang, Shi, Guochao, Li, Qingyun, Zhou, Min, Sayers, Thomas, Tewary, Poonam, Gao, Beili, Wang, Ji Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752504/ https://www.ncbi.nlm.nih.gov/pubmed/29312591 http://dx.doi.org/10.18632/oncotarget.22596 |
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