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Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells

Achaete scute-like 2 (Ascl2) is the Wnt signaling target, its regulation by other signaling is undefined. Now we demonstrated that CD133(+)/CD44(+) cell population from HT-29 or Caco-2 cells exhibited cancer stem cell (CSC) properties with highly expressed Ascl2, which is related to the Hippo signal...

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Detalles Bibliográficos
Autores principales:	Wei, Xiaolong, Ye, Jun, Shang, Yangyang, Chen, Haoyuan, Liu, Shanxi, Liu, Li, Wang, Rongquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752522/ https://www.ncbi.nlm.nih.gov/pubmed/29312609 http://dx.doi.org/10.18632/oncotarget.22673

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