The protease GtgE from Salmonella exclusively targets inactive Rab GTPases

Salmonella infections require the delivery of bacterial effectors into the host cell that alter the regulation of host defense mechanisms. The secreted cysteine protease GtgE from S. Typhimurium manipulates vesicular trafficking by modifying the Rab32 subfamily via cleaving the regulatory switch I r...

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Detalles Bibliográficos
Autores principales: Wachtel, Rudolf, Bräuning, Bastian, Mader, Sophie L., Ecker, Felix, Kaila, Ville R. I., Groll, Michael, Itzen, Aymelt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752668/
https://www.ncbi.nlm.nih.gov/pubmed/29298974
http://dx.doi.org/10.1038/s41467-017-02110-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752668/
https://www.ncbi.nlm.nih.gov/pubmed/29298974
http://dx.doi.org/10.1038/s41467-017-02110-1

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