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The protease GtgE from Salmonella exclusively targets inactive Rab GTPases
Salmonella infections require the delivery of bacterial effectors into the host cell that alter the regulation of host defense mechanisms. The secreted cysteine protease GtgE from S. Typhimurium manipulates vesicular trafficking by modifying the Rab32 subfamily via cleaving the regulatory switch I r...
Autores principales: | Wachtel, Rudolf, Bräuning, Bastian, Mader, Sophie L., Ecker, Felix, Kaila, Ville R. I., Groll, Michael, Itzen, Aymelt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752668/ https://www.ncbi.nlm.nih.gov/pubmed/29298974 http://dx.doi.org/10.1038/s41467-017-02110-1 |
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