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Stricturing Crohn’s disease-like colitis in a patient treated with belatacept

Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) modifying agents have been involved in the development of intestinal inflammation, especially therapeutic monoclonal antibodies directed against CTLA-4. Here we report the appearance of a severe stricturing Crohn’s disease-like colitis in a patien...

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Autores principales: Bozon, Anne, Jeantet, Guillaume, Rivière, Benjamin, Funakoshi, Natalie, Dufour, Gaspard, Combes, Roman, Valats, Jean-Christophe, Delmas, Sylvie, Serre, Jean Emmanuel, Bismuth, Michael, Ramos, Jeanne, Le Quintrec, Moglie, Blanc, Pierre, Pineton de Chambrun, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752725/
https://www.ncbi.nlm.nih.gov/pubmed/29358873
http://dx.doi.org/10.3748/wjg.v23.i48.8660
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author Bozon, Anne
Jeantet, Guillaume
Rivière, Benjamin
Funakoshi, Natalie
Dufour, Gaspard
Combes, Roman
Valats, Jean-Christophe
Delmas, Sylvie
Serre, Jean Emmanuel
Bismuth, Michael
Ramos, Jeanne
Le Quintrec, Moglie
Blanc, Pierre
Pineton de Chambrun, Guillaume
author_facet Bozon, Anne
Jeantet, Guillaume
Rivière, Benjamin
Funakoshi, Natalie
Dufour, Gaspard
Combes, Roman
Valats, Jean-Christophe
Delmas, Sylvie
Serre, Jean Emmanuel
Bismuth, Michael
Ramos, Jeanne
Le Quintrec, Moglie
Blanc, Pierre
Pineton de Chambrun, Guillaume
author_sort Bozon, Anne
collection PubMed
description Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) modifying agents have been involved in the development of intestinal inflammation, especially therapeutic monoclonal antibodies directed against CTLA-4. Here we report the appearance of a severe stricturing Crohn’s disease-like colitis in a patient with a kidney allograft who was treated with belatacept, a recombinant CTLA-4-Ig fusion protein.
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spelling pubmed-57527252018-01-22 Stricturing Crohn’s disease-like colitis in a patient treated with belatacept Bozon, Anne Jeantet, Guillaume Rivière, Benjamin Funakoshi, Natalie Dufour, Gaspard Combes, Roman Valats, Jean-Christophe Delmas, Sylvie Serre, Jean Emmanuel Bismuth, Michael Ramos, Jeanne Le Quintrec, Moglie Blanc, Pierre Pineton de Chambrun, Guillaume World J Gastroenterol Case Report Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) modifying agents have been involved in the development of intestinal inflammation, especially therapeutic monoclonal antibodies directed against CTLA-4. Here we report the appearance of a severe stricturing Crohn’s disease-like colitis in a patient with a kidney allograft who was treated with belatacept, a recombinant CTLA-4-Ig fusion protein. Baishideng Publishing Group Inc 2017-12-28 2017-12-28 /pmc/articles/PMC5752725/ /pubmed/29358873 http://dx.doi.org/10.3748/wjg.v23.i48.8660 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Bozon, Anne
Jeantet, Guillaume
Rivière, Benjamin
Funakoshi, Natalie
Dufour, Gaspard
Combes, Roman
Valats, Jean-Christophe
Delmas, Sylvie
Serre, Jean Emmanuel
Bismuth, Michael
Ramos, Jeanne
Le Quintrec, Moglie
Blanc, Pierre
Pineton de Chambrun, Guillaume
Stricturing Crohn’s disease-like colitis in a patient treated with belatacept
title Stricturing Crohn’s disease-like colitis in a patient treated with belatacept
title_full Stricturing Crohn’s disease-like colitis in a patient treated with belatacept
title_fullStr Stricturing Crohn’s disease-like colitis in a patient treated with belatacept
title_full_unstemmed Stricturing Crohn’s disease-like colitis in a patient treated with belatacept
title_short Stricturing Crohn’s disease-like colitis in a patient treated with belatacept
title_sort stricturing crohn’s disease-like colitis in a patient treated with belatacept
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752725/
https://www.ncbi.nlm.nih.gov/pubmed/29358873
http://dx.doi.org/10.3748/wjg.v23.i48.8660
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