Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification

Matrix assisted laser desorption ionization time of flight (MALDI-TOF) is a powerful analytical tool that has revolutionized microbial identification. Routinely used for bacterial identification, MALDI-TOF has recently been applied to both yeast and filamentous fungi, confirming its pivotal role in...

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Autores principales: Rizzato, Cosmeri, Lombardi, Lisa, Zoppo, Marina, Lupetti, Antonella, Tavanti, Arianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753130/
https://www.ncbi.nlm.nih.gov/pubmed/29376916
http://dx.doi.org/10.3390/jof1030367
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author Rizzato, Cosmeri
Lombardi, Lisa
Zoppo, Marina
Lupetti, Antonella
Tavanti, Arianna
author_facet Rizzato, Cosmeri
Lombardi, Lisa
Zoppo, Marina
Lupetti, Antonella
Tavanti, Arianna
author_sort Rizzato, Cosmeri
collection PubMed
description Matrix assisted laser desorption ionization time of flight (MALDI-TOF) is a powerful analytical tool that has revolutionized microbial identification. Routinely used for bacterial identification, MALDI-TOF has recently been applied to both yeast and filamentous fungi, confirming its pivotal role in the rapid and reliable diagnosis of infections. Subspecies-level identification holds an important role in epidemiological investigations aimed at tracing virulent or drug resistant clones. This review focuses on present and future applications of this versatile tool in the clinical mycology laboratory.
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spelling pubmed-57531302018-01-19 Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification Rizzato, Cosmeri Lombardi, Lisa Zoppo, Marina Lupetti, Antonella Tavanti, Arianna J Fungi (Basel) Review Matrix assisted laser desorption ionization time of flight (MALDI-TOF) is a powerful analytical tool that has revolutionized microbial identification. Routinely used for bacterial identification, MALDI-TOF has recently been applied to both yeast and filamentous fungi, confirming its pivotal role in the rapid and reliable diagnosis of infections. Subspecies-level identification holds an important role in epidemiological investigations aimed at tracing virulent or drug resistant clones. This review focuses on present and future applications of this versatile tool in the clinical mycology laboratory. MDPI 2015-10-16 /pmc/articles/PMC5753130/ /pubmed/29376916 http://dx.doi.org/10.3390/jof1030367 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rizzato, Cosmeri
Lombardi, Lisa
Zoppo, Marina
Lupetti, Antonella
Tavanti, Arianna
Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification
title Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification
title_full Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification
title_fullStr Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification
title_full_unstemmed Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification
title_short Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification
title_sort pushing the limits of maldi-tof mass spectrometry: beyond fungal species identification
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753130/
https://www.ncbi.nlm.nih.gov/pubmed/29376916
http://dx.doi.org/10.3390/jof1030367
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