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STCRDab: the structural T-cell receptor database

The Structural T–cell Receptor Database (STCRDab; http://opig.stats.ox.ac.uk/webapps/stcrdab) is an online resource that automatically collects and curates TCR structural data from the Protein Data Bank. For each entry, the database provides annotations, such as the α/β or γ/δ chain pairings, major...

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Autores principales: Leem, Jinwoo, de Oliveira, Saulo H P, Krawczyk, Konrad, Deane, Charlotte M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753249/
https://www.ncbi.nlm.nih.gov/pubmed/29087479
http://dx.doi.org/10.1093/nar/gkx971
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author Leem, Jinwoo
de Oliveira, Saulo H P
Krawczyk, Konrad
Deane, Charlotte M
author_facet Leem, Jinwoo
de Oliveira, Saulo H P
Krawczyk, Konrad
Deane, Charlotte M
author_sort Leem, Jinwoo
collection PubMed
description The Structural T–cell Receptor Database (STCRDab; http://opig.stats.ox.ac.uk/webapps/stcrdab) is an online resource that automatically collects and curates TCR structural data from the Protein Data Bank. For each entry, the database provides annotations, such as the α/β or γ/δ chain pairings, major histocompatibility complex details, and where available, antigen binding affinities. In addition, the orientation between the variable domains and the canonical forms of the complementarity-determining region loops are also provided. Users can select, view, and download individual or bulk sets of structures based on these criteria. Where available, STCRDab also finds antibody structures that are similar to TCRs, helping users explore the relationship between TCRs and antibodies.
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spelling pubmed-57532492018-01-05 STCRDab: the structural T-cell receptor database Leem, Jinwoo de Oliveira, Saulo H P Krawczyk, Konrad Deane, Charlotte M Nucleic Acids Res Database Issue The Structural T–cell Receptor Database (STCRDab; http://opig.stats.ox.ac.uk/webapps/stcrdab) is an online resource that automatically collects and curates TCR structural data from the Protein Data Bank. For each entry, the database provides annotations, such as the α/β or γ/δ chain pairings, major histocompatibility complex details, and where available, antigen binding affinities. In addition, the orientation between the variable domains and the canonical forms of the complementarity-determining region loops are also provided. Users can select, view, and download individual or bulk sets of structures based on these criteria. Where available, STCRDab also finds antibody structures that are similar to TCRs, helping users explore the relationship between TCRs and antibodies. Oxford University Press 2018-01-04 2017-10-26 /pmc/articles/PMC5753249/ /pubmed/29087479 http://dx.doi.org/10.1093/nar/gkx971 Text en © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Issue
Leem, Jinwoo
de Oliveira, Saulo H P
Krawczyk, Konrad
Deane, Charlotte M
STCRDab: the structural T-cell receptor database
title STCRDab: the structural T-cell receptor database
title_full STCRDab: the structural T-cell receptor database
title_fullStr STCRDab: the structural T-cell receptor database
title_full_unstemmed STCRDab: the structural T-cell receptor database
title_short STCRDab: the structural T-cell receptor database
title_sort stcrdab: the structural t-cell receptor database
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753249/
https://www.ncbi.nlm.nih.gov/pubmed/29087479
http://dx.doi.org/10.1093/nar/gkx971
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