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The European Bioinformatics Institute in 2017: data coordination and integration

The European Bioinformatics Institute (EMBL-EBI) supports life-science research throughout the world by providing open data, open-source software and analytical tools, and technical infrastructure (https://www.ebi.ac.uk). We accommodate an increasingly diverse range of data types and integrate them,...

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Detalles Bibliográficos
Autores principales: Cook, Charles E, Bergman, Mary T, Cochrane, Guy, Apweiler, Rolf, Birney, Ewan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753251/
https://www.ncbi.nlm.nih.gov/pubmed/29186510
http://dx.doi.org/10.1093/nar/gkx1154
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author Cook, Charles E
Bergman, Mary T
Cochrane, Guy
Apweiler, Rolf
Birney, Ewan
author_facet Cook, Charles E
Bergman, Mary T
Cochrane, Guy
Apweiler, Rolf
Birney, Ewan
author_sort Cook, Charles E
collection PubMed
description The European Bioinformatics Institute (EMBL-EBI) supports life-science research throughout the world by providing open data, open-source software and analytical tools, and technical infrastructure (https://www.ebi.ac.uk). We accommodate an increasingly diverse range of data types and integrate them, so that biologists in all disciplines can explore life in ever-increasing detail. We maintain over 40 data resources, many of which are run collaboratively with partners in 16 countries (https://www.ebi.ac.uk/services). Submissions continue to increase exponentially: our data storage has doubled in less than two years to 120 petabytes. Recent advances in cellular imaging and single-cell sequencing techniques are generating a vast amount of high-dimensional data, bringing to light new cell types and new perspectives on anatomy. Accordingly, one of our main focus areas is integrating high-quality information from bioimaging, biobanking and other types of molecular data. This is reflected in our deep involvement in Open Targets, stewarding of plant phenotyping standards (MIAPPE) and partnership in the Human Cell Atlas data coordination platform, as well as the 2017 launch of the Omics Discovery Index. This update gives a birds-eye view of EMBL-EBI’s approach to data integration and service development as genomics begins to enter the clinic.
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spelling pubmed-57532512018-01-05 The European Bioinformatics Institute in 2017: data coordination and integration Cook, Charles E Bergman, Mary T Cochrane, Guy Apweiler, Rolf Birney, Ewan Nucleic Acids Res Database Issue The European Bioinformatics Institute (EMBL-EBI) supports life-science research throughout the world by providing open data, open-source software and analytical tools, and technical infrastructure (https://www.ebi.ac.uk). We accommodate an increasingly diverse range of data types and integrate them, so that biologists in all disciplines can explore life in ever-increasing detail. We maintain over 40 data resources, many of which are run collaboratively with partners in 16 countries (https://www.ebi.ac.uk/services). Submissions continue to increase exponentially: our data storage has doubled in less than two years to 120 petabytes. Recent advances in cellular imaging and single-cell sequencing techniques are generating a vast amount of high-dimensional data, bringing to light new cell types and new perspectives on anatomy. Accordingly, one of our main focus areas is integrating high-quality information from bioimaging, biobanking and other types of molecular data. This is reflected in our deep involvement in Open Targets, stewarding of plant phenotyping standards (MIAPPE) and partnership in the Human Cell Atlas data coordination platform, as well as the 2017 launch of the Omics Discovery Index. This update gives a birds-eye view of EMBL-EBI’s approach to data integration and service development as genomics begins to enter the clinic. Oxford University Press 2018-01-04 2017-11-25 /pmc/articles/PMC5753251/ /pubmed/29186510 http://dx.doi.org/10.1093/nar/gkx1154 Text en © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Issue
Cook, Charles E
Bergman, Mary T
Cochrane, Guy
Apweiler, Rolf
Birney, Ewan
The European Bioinformatics Institute in 2017: data coordination and integration
title The European Bioinformatics Institute in 2017: data coordination and integration
title_full The European Bioinformatics Institute in 2017: data coordination and integration
title_fullStr The European Bioinformatics Institute in 2017: data coordination and integration
title_full_unstemmed The European Bioinformatics Institute in 2017: data coordination and integration
title_short The European Bioinformatics Institute in 2017: data coordination and integration
title_sort european bioinformatics institute in 2017: data coordination and integration
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753251/
https://www.ncbi.nlm.nih.gov/pubmed/29186510
http://dx.doi.org/10.1093/nar/gkx1154
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