Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017

We describe the dynamics of dengue virus (DENV) infection in a woman in her mid-30s who developed fever after returning from Sri Lanka to Italy in April 2017. Laboratory testing demonstrated detectable DENV-RNA in plasma, urine, saliva, vaginal secretion. Persistent shedding of DENV-RNA was demonstr...

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Autores principales: Iannetta, Marco, Lalle, Eleonora, Musso, Maria, Carletti, Fabrizio, Scorzolini, Laura, D’Abramo, Alessandra, Chinello, Pierangelo, Castilletti, Concetta, Ippolito, Giuseppe, Capobianchi, Maria R, Nicastri, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2017
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753441/
https://www.ncbi.nlm.nih.gov/pubmed/28857045
http://dx.doi.org/10.2807/1560-7917.ES.2017.22.34.30600
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author Iannetta, Marco
Lalle, Eleonora
Musso, Maria
Carletti, Fabrizio
Scorzolini, Laura
D’Abramo, Alessandra
Chinello, Pierangelo
Castilletti, Concetta
Ippolito, Giuseppe
Capobianchi, Maria R
Nicastri, Emanuele
author_facet Iannetta, Marco
Lalle, Eleonora
Musso, Maria
Carletti, Fabrizio
Scorzolini, Laura
D’Abramo, Alessandra
Chinello, Pierangelo
Castilletti, Concetta
Ippolito, Giuseppe
Capobianchi, Maria R
Nicastri, Emanuele
author_sort Iannetta, Marco
collection PubMed
description We describe the dynamics of dengue virus (DENV) infection in a woman in her mid-30s who developed fever after returning from Sri Lanka to Italy in April 2017. Laboratory testing demonstrated detectable DENV-RNA in plasma, urine, saliva, vaginal secretion. Persistent shedding of DENV-RNA was demonstrated in vaginal secretion, and DENV-RNA was detectable in the pelleted fraction up to 18 days from symptom onset. These findings give new insights into DENV vaginal shedding and vertical transmission.
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spelling pubmed-57534412018-01-05 Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017 Iannetta, Marco Lalle, Eleonora Musso, Maria Carletti, Fabrizio Scorzolini, Laura D’Abramo, Alessandra Chinello, Pierangelo Castilletti, Concetta Ippolito, Giuseppe Capobianchi, Maria R Nicastri, Emanuele Euro Surveill Rapid Communication We describe the dynamics of dengue virus (DENV) infection in a woman in her mid-30s who developed fever after returning from Sri Lanka to Italy in April 2017. Laboratory testing demonstrated detectable DENV-RNA in plasma, urine, saliva, vaginal secretion. Persistent shedding of DENV-RNA was demonstrated in vaginal secretion, and DENV-RNA was detectable in the pelleted fraction up to 18 days from symptom onset. These findings give new insights into DENV vaginal shedding and vertical transmission. European Centre for Disease Prevention and Control (ECDC) 2017-08-24 /pmc/articles/PMC5753441/ /pubmed/28857045 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.34.30600 Text en This article is copyright of The Authors, 2017. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Iannetta, Marco
Lalle, Eleonora
Musso, Maria
Carletti, Fabrizio
Scorzolini, Laura
D’Abramo, Alessandra
Chinello, Pierangelo
Castilletti, Concetta
Ippolito, Giuseppe
Capobianchi, Maria R
Nicastri, Emanuele
Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017
title Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017
title_full Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017
title_fullStr Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017
title_full_unstemmed Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017
title_short Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017
title_sort persistent detection of dengue virus rna in vaginal secretion of a woman returning from sri lanka to italy, april 2017
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753441/
https://www.ncbi.nlm.nih.gov/pubmed/28857045
http://dx.doi.org/10.2807/1560-7917.ES.2017.22.34.30600
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