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SGLT-2-inhibition with dapagliflozin reduces tissue sodium content: a randomised controlled trial

BACKGROUND AND AIMS: Sodium tissue content by (23)Na magnetic resonance imaging (Na-MRI) has been validated in experimental and human studies. SGLT-2 inhibition blocks the reabsorption of glucose and of sodium in the proximal tubular cells in a 1:1 fashion. We hypothesized that SGLT-2 inhibition in...

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Detalles Bibliográficos
Autores principales:	Karg, M. V., Bosch, A., Kannenkeril, D., Striepe, K., Ott, C., Schneider, M. P., Boemke-Zelch, F., Linz, P., Nagel, A. M., Titze, J., Uder, M., Schmieder, R. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753452/ https://www.ncbi.nlm.nih.gov/pubmed/29301520 http://dx.doi.org/10.1186/s12933-017-0654-z

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