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Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in intracerebral hemorrhage mice
BACKGROUND: Inflammasomes are involved in diverse inflammatory diseases. Previous study reported that the neurotransmitter dopamine inhibited NLRP3 inflammasome activation via dopamine D1 receptor (DRD1). The present study aims to investigate the role of DRD1 on neuroinflammation in intracerebral he...
Autores principales: | Wang, Tian, Nowrangi, Derek, Yu, Lingyan, Lu, Tai, Tang, Jiping, Han, Bing, Ding, Yuxin, Fu, Fenghua, Zhang, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753458/ https://www.ncbi.nlm.nih.gov/pubmed/29301581 http://dx.doi.org/10.1186/s12974-017-1039-7 |
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