Pyroglutamate and Isoaspartate modified Amyloid-Beta in ageing and Alzheimer’s disease

Alzheimer’s disease (AD) is the most common cause of dementia among older adults. Accumulation of amyloid-β (Aβ) in the brain is considered central in AD pathogenesis and its understanding crucial for developing new diagnostic and therapeutic approaches. Recent literature suggests that ageing may in...

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Detalles Bibliográficos
Autores principales: Moro, Maria Luisa, Phillips, Andrew Stephen, Gaimster, Katie, Paul, Christian, Mudher, Amritpal, Nicoll, James A. R., Boche, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753481/
https://www.ncbi.nlm.nih.gov/pubmed/29298722
http://dx.doi.org/10.1186/s40478-017-0505-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753481/
https://www.ncbi.nlm.nih.gov/pubmed/29298722
http://dx.doi.org/10.1186/s40478-017-0505-x

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