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Role of the indoleamine-2,3-dioxygenase/kynurenine pathway of tryptophan metabolism in behavioral alterations in a hepatic encephalopathy rat model

BACKGROUND: This study aims to explore the role of indoleamine-2,3-dioxygenase (IDO)/kynurenine (KYN) pathway of tryptophan (TRY) metabolism in behavioral alterations observed in hepatic encephalopathy (HE) rats. METHODS: Expression levels of proinflammatory cytokines were tested by QT-PCR and ELISA...

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Detalles Bibliográficos
Autores principales:	Jiang, Xi, Xu, Lexing, Tang, Lin, Liu, Fuhe, Chen, Ziwei, Zhang, Jiajia, Chen, Lei, Pang, Cong, Yu, Xuefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753541/ https://www.ncbi.nlm.nih.gov/pubmed/29301550 http://dx.doi.org/10.1186/s12974-017-1037-9

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