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Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique
There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a ne...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753559/ https://www.ncbi.nlm.nih.gov/pubmed/28303807 http://dx.doi.org/10.4103/aja.aja_1_17 |
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author | Yang, Dae Yul Ko, Kyungtae Lee, Seong Ho Moon, Du Geon Kim, Jong Wook Lee, Won Ki |
author_facet | Yang, Dae Yul Ko, Kyungtae Lee, Seong Ho Moon, Du Geon Kim, Jong Wook Lee, Won Ki |
author_sort | Yang, Dae Yul |
collection | PubMed |
description | There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 min and 6.6 ± 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 ± 3.5 cm(2) and 33.6 ± 5.4 cm(2), respectively, representing a mean increase of 68.7% ± 14.0% (P < 0.001). Sixteen individuals (88.9%) were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation. |
format | Online Article Text |
id | pubmed-5753559 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-57535592018-01-05 Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique Yang, Dae Yul Ko, Kyungtae Lee, Seong Ho Moon, Du Geon Kim, Jong Wook Lee, Won Ki Asian J Androl Original Article There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 min and 6.6 ± 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 ± 3.5 cm(2) and 33.6 ± 5.4 cm(2), respectively, representing a mean increase of 68.7% ± 14.0% (P < 0.001). Sixteen individuals (88.9%) were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation. Medknow Publications & Media Pvt Ltd 2018 2017-03-10 /pmc/articles/PMC5753559/ /pubmed/28303807 http://dx.doi.org/10.4103/aja.aja_1_17 Text en Copyright: © The Author(s)(2017) http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Yang, Dae Yul Ko, Kyungtae Lee, Seong Ho Moon, Du Geon Kim, Jong Wook Lee, Won Ki Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique |
title | Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique |
title_full | Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique |
title_fullStr | Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique |
title_full_unstemmed | Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique |
title_short | Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique |
title_sort | efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753559/ https://www.ncbi.nlm.nih.gov/pubmed/28303807 http://dx.doi.org/10.4103/aja.aja_1_17 |
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