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Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique

There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a ne...

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Autores principales: Yang, Dae Yul, Ko, Kyungtae, Lee, Seong Ho, Moon, Du Geon, Kim, Jong Wook, Lee, Won Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753559/
https://www.ncbi.nlm.nih.gov/pubmed/28303807
http://dx.doi.org/10.4103/aja.aja_1_17
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author Yang, Dae Yul
Ko, Kyungtae
Lee, Seong Ho
Moon, Du Geon
Kim, Jong Wook
Lee, Won Ki
author_facet Yang, Dae Yul
Ko, Kyungtae
Lee, Seong Ho
Moon, Du Geon
Kim, Jong Wook
Lee, Won Ki
author_sort Yang, Dae Yul
collection PubMed
description There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 min and 6.6 ± 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 ± 3.5 cm(2) and 33.6 ± 5.4 cm(2), respectively, representing a mean increase of 68.7% ± 14.0% (P < 0.001). Sixteen individuals (88.9%) were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation.
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spelling pubmed-57535592018-01-05 Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique Yang, Dae Yul Ko, Kyungtae Lee, Seong Ho Moon, Du Geon Kim, Jong Wook Lee, Won Ki Asian J Androl Original Article There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 min and 6.6 ± 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 ± 3.5 cm(2) and 33.6 ± 5.4 cm(2), respectively, representing a mean increase of 68.7% ± 14.0% (P < 0.001). Sixteen individuals (88.9%) were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation. Medknow Publications & Media Pvt Ltd 2018 2017-03-10 /pmc/articles/PMC5753559/ /pubmed/28303807 http://dx.doi.org/10.4103/aja.aja_1_17 Text en Copyright: © The Author(s)(2017) http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Yang, Dae Yul
Ko, Kyungtae
Lee, Seong Ho
Moon, Du Geon
Kim, Jong Wook
Lee, Won Ki
Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique
title Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique
title_full Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique
title_fullStr Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique
title_full_unstemmed Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique
title_short Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique
title_sort efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753559/
https://www.ncbi.nlm.nih.gov/pubmed/28303807
http://dx.doi.org/10.4103/aja.aja_1_17
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