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cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue

Induction of immunoglobulin (Ig) A in the mucosa of the upper respiratory tract and the nasal cavity protects against influenza virus infection. Cyclic dinucleotides (CDNs) are used as mucosal adjuvants to enhance the immunogenicity of intranasal influenza hemagglutinin (HA) vaccines. The adjuvant a...

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Detalles Bibliográficos
Autores principales:	Takaki, Hiromi, Takashima, Ken, Oshiumi, Hiroyuki, Ainai, Akira, Suzuki, Tadaki, Hasegawa, Hideki, Matsumoto, Misako, Seya, Tsukasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753664/ https://www.ncbi.nlm.nih.gov/pubmed/29258267 http://dx.doi.org/10.3390/medsci5040035

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