Treatment of severe hypocalcaemia due to osteoblastic metastases in a patient with post-thyroidectomy hypoparathyroidism with (153)Sm-EDTMP

Symptomatic hypocalcaemia is an uncommon finding in patients with malignant tumours. We describe a patient with advanced metastatic breast cancer who developed severe hypocalcaemia caused by the combination of osteoblastic metastases and a permanent postoperative hypoparathyroidism. The patient fail...

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Detalles Bibliográficos
Autores principales: Kassi, Eva, Kapsali, Ifigeneia, Kokkinos, Michalis, Gogas, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Case Reports 2017
Materias:
Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753734/
https://www.ncbi.nlm.nih.gov/pubmed/28512123
http://dx.doi.org/10.1136/bcr-2017-219354
Descripción
Sumario:Symptomatic hypocalcaemia is an uncommon finding in patients with malignant tumours. We describe a patient with advanced metastatic breast cancer who developed severe hypocalcaemia caused by the combination of osteoblastic metastases and a permanent postoperative hypoparathyroidism. The patient failed to be treated with the conventional replacement therapy and was submitted effectively to radionucleotide therapy with (153)Sm.

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