Cargando…

Thrombin generation correlates with disease duration in multiple sclerosis (MS): Novel insights into the MS-associated prothrombotic state

BACKGROUND: Thrombin is well recognised for its role in the coagulation cascade but it also plays a role in inflammation, with enhanced thrombin generation observed in several inflammatory disorders. Although patients with multiple sclerosis (MS) have a higher incidence of thrombotic disease, thromb...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parsons, Martin EM, O’Connell, Karen, Allen, Seamus, Egan, Karl, Szklanna, Paulina B, McGuigan, Christopher, Ní Áinle, Fionnuala, Maguire, Patricia B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2017
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753921/ https://www.ncbi.nlm.nih.gov/pubmed/29318029 http://dx.doi.org/10.1177/2055217317747624

Ejemplares similares

A Protocol for Improved Precision and Increased Confidence in Nanoparticle Tracking Analysis Concentration Measurements between 50 and 120 nm in Biological Fluids
por: Parsons, Martin E. M., et al.
Publicado: (2017)

Liver stiffness and thrombin generation in compensated cirrhosis
por: Dillon, Audrey, et al.
Publicado: (2019)

Endothelial barrier protective properties of low molecular weight heparin: A novel potential tool in the prevention of cancer metastasis?
por: Kevane, Barry, et al.
Publicado: (2017)

Increased expression of Tbet in CD4(+) T cells from clinically isolated syndrome patients at high risk of conversion to clinically definite MS
por: Basdeo, Sharee A., et al.
Publicado: (2016)

An optimized protocol to isolate quiescent washed platelets from human whole blood and generate platelet releasate under clinical conditions
por: Weiss, Luisa, et al.
Publicado: (2023)

COVID-19 Is Associated with Endothelial Dysfunction and Enhanced Plasma Thrombin Generation Despite Pharmacological Thromboprophylaxis
por: Kelliher, Sarah, et al.
Publicado: (2021)

Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease
por: Maguire, Patricia B., et al.
Publicado: (2020)

The canine activated platelet secretome (CAPS): A translational model of thrombin‐evoked platelet activation response
por: Cremer, Signe E., et al.
Publicado: (2020)

The Prothrombotic Phenotypes in Familial Protein C Deficiency Are Differentiated by Computational Modeling of Thrombin Generation
por: Brummel-Ziedins, Kathleen E., et al.
Publicado: (2012)

Development and validation of an analytical method for the determination of direct oral anticoagulants (DOAC) and the direct thrombin-inhibitor argatroban by HPLC–MS/MS
por: Brückner, Lea, et al.
Publicado: (2021)

Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells
por: Grande, Rosalia, et al.
Publicado: (2019)

Smouldering multiple sclerosis: the ‘real MS’
por: Giovannoni, Gavin, et al.
Publicado: (2022)

Effects of Heparin and Bivalirudin on Thrombin-Induced Platelet Activation: Differential Modulation of PAR Signaling Drives Divergent Prothrombotic Responses
por: Lund, Mikael, et al.
Publicado: (2021)

HPLC-MS/MS Oxylipin Analysis of Plasma from Amyotrophic Lateral Sclerosis Patients
por: Mastrogiovanni, Mauricio, et al.
Publicado: (2022)

Uveitis prior to clinical presentation of Multiple Sclerosis (MS) is associated with better MS prognosis
por: Raskin, Eyal, et al.
Publicado: (2022)

AZD-1222/elasomeran/tozinameran: Multiple sclerosis (MS) and relapse of MS: 16 case reports
Publicado: (2022)

Characteristics, comorbidities, and complications in multiple sclerosis (MS) and non-MS patients undergoing lumbar fusion for deformity
por: Sulovari, Aron, et al.
Publicado: (2023)

Comparison of Flow Injection-MS/MS and LC-MS/MS for the Determination of Ochratoxin A
por: Zhang, Kai
Publicado: (2021)

The MS-DOS handbook
por: King, Richard Allen
Publicado: (1985)

Characterization of thrombin/factor Xa inhibitors in Rhizoma Chuanxiong through UPLC-MS-based multivariate statistical analysis
por: Yang, Yi-Yao, et al.
Publicado: (2020)

Evaluation of Protein Purification Techniques and Effects of Storage Duration on LC-MS/MS Analysis of Archived FFPE Human CRC Tissues
por: Rossouw, Sophia C., et al.
Publicado: (2021)

Proinflammatory and Prothrombotic Effects of Hypoglycemia
por: Dandona, Paresh, et al.
Publicado: (2010)

Largazole Pharmacokinetics in Rats by LC-MS/MS
por: Yu, Mingming, et al.
Publicado: (2014)

Determination of Nine Fentanyl Drugs in Hair Samples by GC-MS/MS and LC-MS/MS
por: Wei, Qi, et al.
Publicado: (2022)

Determination of 355 Pesticides in Lemon and Lemon Juice by LC-MS/MS and GC-MS/MS
por: Aslantas, Sule, et al.
Publicado: (2023)

Emotional Intelligence (EI) of Patients with Multiple Sclerosis (MS)
por: GHAJARZADEH, Mahsa, et al.
Publicado: (2014)

Stepchild or Prodigy? Neuroprotection in Multiple Sclerosis (MS) Research
por: Rottlaender, Andrea, et al.
Publicado: (2015)

Prevalence of Multiple Sclerosis (MS) in Zanjan Province of Iran
por: Ghajarzadeh, Mahsa, et al.
Publicado: (2020)

Neutrophils: Underestimated Players in the Pathogenesis of Multiple Sclerosis (MS)
por: De Bondt, Mirre, et al.
Publicado: (2020)

A combination of Q-TOF LC/MS and LC-MS/MS based metabolomics in pediatric-onset multiple sclerosis demonstrates potential biomarkers for unclassified patients
por: SOLMAZ, İsmail, et al.
Publicado: (2022)

Quantification of Degradation Products Formed during Heat Sterilization of Glucose Solutions by LC-MS/MS: Impact of Autoclaving Temperature and Duration on Degradation
por: Leitzen, Sarah, et al.
Publicado: (2021)

Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) following COVID-19 vaccines: A systematic review
por: Mirmosayyeb, O., et al.
Publicado: (2023)

Migraine is comorbid with multiple sclerosis and associated with a more symptomatic MS course
por: Kister, Ilya, et al.
Publicado: (2010)

Determination of 77 Multiclass Pesticides and Their Metabolitesin Capsicum and Tomato Using GC-MS/MS and LC-MS/MS
por: Naik Rathod, Harischandra, et al.
Publicado: (2021)

Implications of Lymphocyte Anergy to Glycolipids in Multiple Sclerosis (MS): iNKT Cells May Mediate the MS Infectious Trigger
por: Hogan, Edward L, et al.
Publicado: (2013)

Lipidomic UPLC-MS/MS Profiles of Normal-Appearing White Matter Differentiate Primary and Secondary Progressive Multiple Sclerosis
por: Pousinis, Petros, et al.
Publicado: (2020)

Does the multiple sclerosis (MS) map need to change again? An update of MS prevalence in Mazandaran province of Iran in 2018
por: Baghbanian, Seyed Mohammad, et al.
Publicado: (2020)

2304: Identifying optimal multiple sclerosis (MS)-specific atrophy markers as primary endpoint for Phase II s in progressive MS
por: Azevedo, Christina, et al.
Publicado: (2018)

Nutritional status of multiple sclerosis (MS) patients attending Kasr Alainy MS unit: an exploratory cross-sectional study
por: Afifi, Zeinab E., et al.
Publicado: (2021)

Good multiple sclerosis (MS) care and how to get there in Canada: Perspectives of Canadian healthcare providers working with persons with MS
por: Petrin, Julie, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2oripbeikk0nr0ub3bqc9uduih