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Nano-Encapsulation of Bilirubin in Pluronic F127–Chitosan Improves Uptake in β Cells and Increases Islet Viability and Function after Hypoxic Stress
Pancreatic islet transplantation is the only curative, noninvasive treatment for type 1 diabetes mellitus; however, high rates of cell death in the immediate postimplantation period have limited the success of this procedure. Bilirubin, an endogenous antioxidant, can improve the survival of murine p...
Autores principales: | Fullagar, Bronwyn, Rao, Wei, Gilor, Chen, Xu, Feng, He, Xiaoming, Adin, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753985/ https://www.ncbi.nlm.nih.gov/pubmed/29251115 http://dx.doi.org/10.1177/0963689717735112 |
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