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Quantitative systems toxicology

The overarching goal of modern drug development is to optimize therapeutic benefits while minimizing adverse effects. However, inadequate efficacy and safety concerns remain to be the major causes of drug attrition in clinical development. For the past 80 years, toxicity testing has consisted of eva...

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Detalles Bibliográficos
Autores principales: Bloomingdale, Peter, Housand, Conrad, Apgar, Joshua F., Millard, Bjorn L., Mager, Donald E., Burke, John M., Shah, Dhaval K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754001/
https://www.ncbi.nlm.nih.gov/pubmed/29308440
http://dx.doi.org/10.1016/j.cotox.2017.07.003