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Tramadol-Induced Hiccups: A Report of Two Cases

Hiccups can be idiopathic, psychogenic and organic, with drugs being one of the most important causes of hiccups. Although the exact pathophysiological processes involved are still poorly understood, the neurotransmitters dopamine, serotonin, and γ-aminobutyric acid (GABA) have been documented to pl...

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Autores principales: Panchal, Radhika, Bhutt, Vishal, Anovadiya, Ashish, Purohit, Bhargav, Dekhaiya, Firdaus, Goswami, Nutanbala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754278/
https://www.ncbi.nlm.nih.gov/pubmed/29302825
http://dx.doi.org/10.1007/s40800-017-0066-8
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author Panchal, Radhika
Bhutt, Vishal
Anovadiya, Ashish
Purohit, Bhargav
Dekhaiya, Firdaus
Goswami, Nutanbala
author_facet Panchal, Radhika
Bhutt, Vishal
Anovadiya, Ashish
Purohit, Bhargav
Dekhaiya, Firdaus
Goswami, Nutanbala
author_sort Panchal, Radhika
collection PubMed
description Hiccups can be idiopathic, psychogenic and organic, with drugs being one of the most important causes of hiccups. Although the exact pathophysiological processes involved are still poorly understood, the neurotransmitters dopamine, serotonin, and γ-aminobutyric acid (GABA) have been documented to play a significant role in the generation of hiccups. We report on two patients with cellulitis who developed hiccups with the use of tramadol as an analgesic. The possible mechanisms and clinical implications of this rare adverse event are discussed. Both patients recovered from the hiccups with the use of baclofen tablets.
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spelling pubmed-57542782018-01-22 Tramadol-Induced Hiccups: A Report of Two Cases Panchal, Radhika Bhutt, Vishal Anovadiya, Ashish Purohit, Bhargav Dekhaiya, Firdaus Goswami, Nutanbala Drug Saf Case Rep Case Report Hiccups can be idiopathic, psychogenic and organic, with drugs being one of the most important causes of hiccups. Although the exact pathophysiological processes involved are still poorly understood, the neurotransmitters dopamine, serotonin, and γ-aminobutyric acid (GABA) have been documented to play a significant role in the generation of hiccups. We report on two patients with cellulitis who developed hiccups with the use of tramadol as an analgesic. The possible mechanisms and clinical implications of this rare adverse event are discussed. Both patients recovered from the hiccups with the use of baclofen tablets. Springer International Publishing 2018-01-05 /pmc/articles/PMC5754278/ /pubmed/29302825 http://dx.doi.org/10.1007/s40800-017-0066-8 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Case Report
Panchal, Radhika
Bhutt, Vishal
Anovadiya, Ashish
Purohit, Bhargav
Dekhaiya, Firdaus
Goswami, Nutanbala
Tramadol-Induced Hiccups: A Report of Two Cases
title Tramadol-Induced Hiccups: A Report of Two Cases
title_full Tramadol-Induced Hiccups: A Report of Two Cases
title_fullStr Tramadol-Induced Hiccups: A Report of Two Cases
title_full_unstemmed Tramadol-Induced Hiccups: A Report of Two Cases
title_short Tramadol-Induced Hiccups: A Report of Two Cases
title_sort tramadol-induced hiccups: a report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754278/
https://www.ncbi.nlm.nih.gov/pubmed/29302825
http://dx.doi.org/10.1007/s40800-017-0066-8
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