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Tramadol-Induced Hiccups: A Report of Two Cases
Hiccups can be idiopathic, psychogenic and organic, with drugs being one of the most important causes of hiccups. Although the exact pathophysiological processes involved are still poorly understood, the neurotransmitters dopamine, serotonin, and γ-aminobutyric acid (GABA) have been documented to pl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754278/ https://www.ncbi.nlm.nih.gov/pubmed/29302825 http://dx.doi.org/10.1007/s40800-017-0066-8 |
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author | Panchal, Radhika Bhutt, Vishal Anovadiya, Ashish Purohit, Bhargav Dekhaiya, Firdaus Goswami, Nutanbala |
author_facet | Panchal, Radhika Bhutt, Vishal Anovadiya, Ashish Purohit, Bhargav Dekhaiya, Firdaus Goswami, Nutanbala |
author_sort | Panchal, Radhika |
collection | PubMed |
description | Hiccups can be idiopathic, psychogenic and organic, with drugs being one of the most important causes of hiccups. Although the exact pathophysiological processes involved are still poorly understood, the neurotransmitters dopamine, serotonin, and γ-aminobutyric acid (GABA) have been documented to play a significant role in the generation of hiccups. We report on two patients with cellulitis who developed hiccups with the use of tramadol as an analgesic. The possible mechanisms and clinical implications of this rare adverse event are discussed. Both patients recovered from the hiccups with the use of baclofen tablets. |
format | Online Article Text |
id | pubmed-5754278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-57542782018-01-22 Tramadol-Induced Hiccups: A Report of Two Cases Panchal, Radhika Bhutt, Vishal Anovadiya, Ashish Purohit, Bhargav Dekhaiya, Firdaus Goswami, Nutanbala Drug Saf Case Rep Case Report Hiccups can be idiopathic, psychogenic and organic, with drugs being one of the most important causes of hiccups. Although the exact pathophysiological processes involved are still poorly understood, the neurotransmitters dopamine, serotonin, and γ-aminobutyric acid (GABA) have been documented to play a significant role in the generation of hiccups. We report on two patients with cellulitis who developed hiccups with the use of tramadol as an analgesic. The possible mechanisms and clinical implications of this rare adverse event are discussed. Both patients recovered from the hiccups with the use of baclofen tablets. Springer International Publishing 2018-01-05 /pmc/articles/PMC5754278/ /pubmed/29302825 http://dx.doi.org/10.1007/s40800-017-0066-8 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Case Report Panchal, Radhika Bhutt, Vishal Anovadiya, Ashish Purohit, Bhargav Dekhaiya, Firdaus Goswami, Nutanbala Tramadol-Induced Hiccups: A Report of Two Cases |
title | Tramadol-Induced Hiccups: A Report of Two Cases |
title_full | Tramadol-Induced Hiccups: A Report of Two Cases |
title_fullStr | Tramadol-Induced Hiccups: A Report of Two Cases |
title_full_unstemmed | Tramadol-Induced Hiccups: A Report of Two Cases |
title_short | Tramadol-Induced Hiccups: A Report of Two Cases |
title_sort | tramadol-induced hiccups: a report of two cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754278/ https://www.ncbi.nlm.nih.gov/pubmed/29302825 http://dx.doi.org/10.1007/s40800-017-0066-8 |
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