Cargando…

CRTC2 promotes non‐small cell lung cancer A549 migration and invasion in vitro

BACKGROUND: CRTC2 is highly expressed in lung cancer and contributes to lung cancer pathogenesis; however, whether CRTC2 promotes lung cancer metastasis remains unknown. In the present study, we investigated the role of CRTC2 in lung cancer metastasis in vitro. METHODS: CRTC2 stable knockdown of lun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Shaoqing, Luo, Wei, Zhang, Rui, Wang, Chu, Zheng, Yuanyuan, Song, Yunhua, Wang, Rongchun, Zhang, Liyan, Zhang, Lihua, Li, Weimin, Luo, Zhuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754302/ https://www.ncbi.nlm.nih.gov/pubmed/29105369 http://dx.doi.org/10.1111/1759-7714.12550

Ejemplares similares

Phosphorylation of CREB-Specific Coactivator CRTC2 at Ser238 Promotes Proliferation, Migration, and Invasion of Colorectal Cancer Cells
por: Wang, Yi, et al.
Publicado: (2020)

Identification and validation of PROM1 and CRTC2 mutations in lung cancer patients
por: He, Yanqi, et al.
Publicado: (2014)

Metformin induces apoptotic cytotoxicity depending on AMPK/PKA/GSK-3β-mediated c-FLIP(L) degradation in non-small cell lung cancer
por: Luo, Zhuang, et al.
Publicado: (2019)

Silencing BMP-2 expression inhibits A549 and H460 cell proliferation and migration
por: Chu, Heying, et al.
Publicado: (2014)

PRDX6 Overexpression Promotes Proliferation, Invasion, and Migration of A549 Cells in vitro and in vivo
por: Li, Hao, et al.
Publicado: (2021)

Cadmium induces A549 cell migration and invasion by activating ERK
por: Zhai, Huijuan, et al.
Publicado: (2019)

STIM1 silencing inhibits the migration and invasion of A549 cells
por: Wang, Yadong, et al.
Publicado: (2017)

SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro
por: Zhang, Siyang, et al.
Publicado: (2008)

Neutrophil Extracellular Traps Facilitate A549 Cell Invasion and Migration in a Macrophage-Maintained Inflammatory Microenvironment
por: Zhang, Lemeng, et al.
Publicado: (2022)

Sam68 promotes hepatic gluconeogenesis via CRTC2
por: Qiao, Aijun, et al.
Publicado: (2021)

CRTC2 modulates hepatic SREBP1c cleavage by controlling Insig2a expression during fasting
por: Zhang, Yuanyuan, et al.
Publicado: (2018)

Novel role for the CRTC2 in lipid homeostasis
por: Matsuzaka, Takashi, et al.
Publicado: (2016)

Activation of the adipocyte CREB/CRTC pathway in obesity
por: Yoon, Young-Sil, et al.
Publicado: (2021)

Novel role of AMPK in cocaine reinforcement via regulating CRTC1
por: Liu, Xiao-Xing, et al.
Publicado: (2022)

Crtc1 Deficiency Causes Obesity Potentially via Regulating PPARγ Pathway in White Adipose
por: Hu, Yimeng, et al.
Publicado: (2021)

Alpha-mangostin inhibits the migration and invasion of A549 lung cancer cells
por: Phan, Thi Kieu Trang, et al.
Publicado: (2018)

Isorhamnetin inhibited migration and invasion via suppression of Akt/ERK-mediated epithelial-to-mesenchymal transition (EMT) in A549 human non-small-cell lung cancer cells
por: Luo, Wei, et al.
Publicado: (2019)

Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway
por: Zhang, Xing, et al.
Publicado: (2018)

Adipose mTORC1 suppresses prostaglandin signaling and beige adipogenesis via the CRTC2-COX-2 pathway
por: Zhang, Xing, et al.
Publicado: (2021)

Accuracy of interleukin-27 assay for the diagnosis of tuberculous pleurisy: A PRISMA-compliant meta-analysis
por: Li, Min, et al.
Publicado: (2017)

A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP‐2
por: Li, Yujie, et al.
Publicado: (2017)

Requirement of CRTC1 coactivator for hepatitis B virus transcription
por: Tang, Hei-Man Vincent, et al.
Publicado: (2014)

The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila
por: Yin, Youjie, et al.
Publicado: (2022)

The CREB Coactivator CRTC2 Links Hepatic ER Stress and Fasting Gluconeogenesis
por: Wang, Yiguo, et al.
Publicado: (2009)

EGF Induces Migration Independent of EMT or Invasion in A549 Lung Adenocarcinoma Cells
por: Schelch, Karin, et al.
Publicado: (2021)

A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex
por: Chen, Yaqiong, et al.
Publicado: (2022)

Comprehensive evaluation of the metabolic effects of porcine CRTC3 overexpression on subcutaneous adipocytes with metabolomic and transcriptomic analyses
por: Liu, Jiaqi, et al.
Publicado: (2021)

Suppression of CRTC2-mediated hepatic gluconeogenesis by TRAF6 contributes to hypoglycemia in septic shock
por: Lv, Sihan, et al.
Publicado: (2016)

Effect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study
por: Wang, Yanyan, et al.
Publicado: (2009)

In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma
por: Li, Li, et al.
Publicado: (2023)

The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non–small cell lung cancer
por: Rodón, Laura, et al.
Publicado: (2019)

CRTC2 activates the epithelial–mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway
por: Li, Yujie, et al.
Publicado: (2023)

The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock
por: Jagannath, Aarti, et al.
Publicado: (2013)

CRTC1 gene is differentially methylated in the human hippocampus in Alzheimer’s disease
por: Mendioroz, Maite, et al.
Publicado: (2016)

Epigenetic regulation of Fgf1 transcription by CRTC1 and memory enhancement
por: Uchida, Shusaku, et al.
Publicado: (2018)

Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary Disorder
por: Yun, Cheong-Yong, et al.
Publicado: (2019)

Disruption of CRTC1 and CRTC2 in Sim1 cells strongly increases high-fat diet intake in female mice but has a modest impact on male mice
por: Tanaka, Jin, et al.
Publicado: (2022)

Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3
por: Shan, Tizhong, et al.
Publicado: (2016)

Metformin mediated microRNA-7 upregulation inhibits growth, migration, and invasion of non-small cell lung cancer A549 cells
por: Dong, Jingying, et al.
Publicado: (2020)

Anti-proliferative, anti-migration, and anti-invasion activity of novel hesperidin glycosides in non-small cell lung cancer A549 cells
por: Poomipark, Natwadee, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_udb3e223v9o9n3c4gr1qncrbaq