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Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors

One challenge for synthetic biologists is the predictable tuning of genetic circuit regulatory components to elicit desired outputs. Gene expression driven by ligand-inducible transcription factor systems must exhibit the correct ON and OFF characteristics: appropriate activation and leakiness in th...

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Detalles Bibliográficos
Autores principales:	Chen, Ye, Ho, Joanne M. L., Shis, David L., Gupta, Chinmaya, Long, James, Wagner, Daniel S., Ott, William, Josić, Krešimir, Bennett, Matthew R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754348/ https://www.ncbi.nlm.nih.gov/pubmed/29302024 http://dx.doi.org/10.1038/s41467-017-02473-5

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