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Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts

CRISPR–Cas systems offer an immune mechanism through which prokaryotic hosts can acquire heritable resistance to genetic parasites, including temperate phages. Co-transcriptional DNA and RNA targeting by type III-A CRISPR–Cas systems restricts temperate phage lytic infections while allowing lysogeni...

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Detalles Bibliográficos
Autores principales:	Goldberg, Gregory W., McMillan, Elizabeth A., Varble, Andrew, Modell, Joshua W., Samai, Poulami, Jiang, Wenyan, Marraffini, Luciano A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754349/ https://www.ncbi.nlm.nih.gov/pubmed/29302058 http://dx.doi.org/10.1038/s41467-017-02557-2

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