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Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

Proinflammatory eicosanoids (prostaglandins and leukotrienes) and specialized pro-resolving mediators (SPM) are temporally regulated during infections. Here we show that human macrophage phenotypes biosynthesize unique lipid mediator signatures when exposed to pathogenic bacteria. E. coli and S. aur...

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Detalles Bibliográficos
Autores principales:	Werz, Oliver, Gerstmeier, Jana, Libreros, Stephania, De la Rosa, Xavier, Werner, Markus, Norris, Paul C., Chiang, Nan, Serhan, Charles N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754355/ https://www.ncbi.nlm.nih.gov/pubmed/29302056 http://dx.doi.org/10.1038/s41467-017-02538-5

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