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Maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis

INTRODUCTION: In light of inconsistencies in the literature, this study aimed to investigate the relationship between obesity (current and historic) and osteoarthritis (OA) of the knee or hip. MATERIALS AND METHODS: We examined 99 people (knee OA, hip OA and controls), age > 50 years, in a case–c...

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Autores principales: Singer, Sabine Patricia, Dammerer, Dietmar, Krismer, Martin, Liebensteiner, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754409/
https://www.ncbi.nlm.nih.gov/pubmed/29079909
http://dx.doi.org/10.1007/s00402-017-2825-5
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author Singer, Sabine Patricia
Dammerer, Dietmar
Krismer, Martin
Liebensteiner, Michael C.
author_facet Singer, Sabine Patricia
Dammerer, Dietmar
Krismer, Martin
Liebensteiner, Michael C.
author_sort Singer, Sabine Patricia
collection PubMed
description INTRODUCTION: In light of inconsistencies in the literature, this study aimed to investigate the relationship between obesity (current and historic) and osteoarthritis (OA) of the knee or hip. MATERIALS AND METHODS: We examined 99 people (knee OA, hip OA and controls), age > 50 years, in a case–control study. The current weight, height and waist circumference were measured on site, and detailed weight changes over their lifetime were based on questionnaires and standardized interviews. We used binomial logistic regression to determine the predictive value for an osteoarthritis group membership of each derived indicator. RESULTS: An increase in ‘maximum-BMI’ increased the odds ratio for both knee OA (OR 1.2; CI 1.1–1.4; p = 0.005; R (2) = 0.36) and hip OA (OR 1.2; CI 1.0–1.3; p = 0.027; R (2) = 0.16). Current BMI was significantly associated with knee OA but not with hip OA. A high “minimum-BMI” (over the age of 18 years) had the highest odds ratio of all calculated indicators for both osteoarthritis groups. CONCLUSIONS: Based on our findings, it is concluded that the maximum BMI over one’s lifespan is a better predictor of OA of the hip or the knee than the current BMI. The knee joint seems to be more sensitive to obesity as current BMI was associated only with knee OA but not with hip OA.
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spelling pubmed-57544092018-01-22 Maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis Singer, Sabine Patricia Dammerer, Dietmar Krismer, Martin Liebensteiner, Michael C. Arch Orthop Trauma Surg Knee Arthroplasty INTRODUCTION: In light of inconsistencies in the literature, this study aimed to investigate the relationship between obesity (current and historic) and osteoarthritis (OA) of the knee or hip. MATERIALS AND METHODS: We examined 99 people (knee OA, hip OA and controls), age > 50 years, in a case–control study. The current weight, height and waist circumference were measured on site, and detailed weight changes over their lifetime were based on questionnaires and standardized interviews. We used binomial logistic regression to determine the predictive value for an osteoarthritis group membership of each derived indicator. RESULTS: An increase in ‘maximum-BMI’ increased the odds ratio for both knee OA (OR 1.2; CI 1.1–1.4; p = 0.005; R (2) = 0.36) and hip OA (OR 1.2; CI 1.0–1.3; p = 0.027; R (2) = 0.16). Current BMI was significantly associated with knee OA but not with hip OA. A high “minimum-BMI” (over the age of 18 years) had the highest odds ratio of all calculated indicators for both osteoarthritis groups. CONCLUSIONS: Based on our findings, it is concluded that the maximum BMI over one’s lifespan is a better predictor of OA of the hip or the knee than the current BMI. The knee joint seems to be more sensitive to obesity as current BMI was associated only with knee OA but not with hip OA. Springer Berlin Heidelberg 2017-10-27 2018 /pmc/articles/PMC5754409/ /pubmed/29079909 http://dx.doi.org/10.1007/s00402-017-2825-5 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Knee Arthroplasty
Singer, Sabine Patricia
Dammerer, Dietmar
Krismer, Martin
Liebensteiner, Michael C.
Maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis
title Maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis
title_full Maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis
title_fullStr Maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis
title_full_unstemmed Maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis
title_short Maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis
title_sort maximum lifetime body mass index is the appropriate predictor of knee and hip osteoarthritis
topic Knee Arthroplasty
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754409/
https://www.ncbi.nlm.nih.gov/pubmed/29079909
http://dx.doi.org/10.1007/s00402-017-2825-5
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