Cargando…

The iPSYCH2012 case–cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders

The Integrative Psychiatric Research (iPSYCH) consortium has established a large Danish population-based Case–Cohort sample (iPSYCH2012) aimed at unravelling the genetic and environmental architecture of severe mental disorders. The iPSYCH2012 sample is nested within the entire Danish population bor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pedersen, C B, Bybjerg-Grauholm, J, Pedersen, M G, Grove, J, Agerbo, E, Bækvad-Hansen, M, Poulsen, J B, Hansen, C S, McGrath, J J, Als, T D, Goldstein, J I, Neale, B M, Daly, M J, Hougaard, D M, Mors, O, Nordentoft, M, Børglum, A D, Werge, T, Mortensen, P B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754466/ https://www.ncbi.nlm.nih.gov/pubmed/28924187 http://dx.doi.org/10.1038/mp.2017.196

Ejemplares similares

Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample
por: Suppli, Nis P., et al.
Publicado: (2021)

Polygenic risk score, psychosocial environment and the risk of attention-deficit/hyperactivity disorder
por: Østergaard, Søren D., et al.
Publicado: (2020)

Accounting for age of onset and family history improves power in genome-wide association studies
por: Pedersen, Emil M., et al.
Publicado: (2022)

Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis
por: Strom, Nora I., et al.
Publicado: (2021)

Pharmacogenetic genotype and phenotype frequencies in a large Danish population-based case-cohort sample
por: Lunenburg, Carin A. T. C., et al.
Publicado: (2021)

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease
por: Hagen, Christian M., et al.
Publicado: (2018)

Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder
por: Demontis, Ditte, et al.
Publicado: (2021)

Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder
por: Demontis, Ditte, et al.
Publicado: (2021)

Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders
por: Skogstrand, Kristin, et al.
Publicado: (2019)

Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes
por: Bybjerg-Grauholm, Jonas, et al.
Publicado: (2018)

Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome
por: Starnawska, A, et al.
Publicado: (2017)

Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have a similar burden of rare protein-truncating variants
por: Satterstrom, F. Kyle, et al.
Publicado: (2019)

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population
por: Nudel, Ron, et al.
Publicado: (2019)

Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity
por: Rajagopal, Veera M., et al.
Publicado: (2023)

Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study
por: Munch, Tina Nørgaard, et al.
Publicado: (2021)

Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks
por: Appadurai, Vivek, et al.
Publicado: (2023)

Elevated polygenic burden for autism is associated with differential DNA methylation at birth
por: Hannon, Eilis, et al.
Publicado: (2018)

Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction
por: Albiñana, Clara, et al.
Publicado: (2021)

Evaluation of whole genome amplified DNA to decrease material expenditure and increase quality
por: Bækvad-Hansen, Marie, et al.
Publicado: (2017)

A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness
por: Nudel, Ron, et al.
Publicado: (2020)

ADuLT: An efficient and robust time-to-event GWAS
por: Pedersen, Emil M., et al.
Publicado: (2023)

The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement
por: Munch, Tina N, et al.
Publicado: (2023)

A polygenic resilience score moderates the genetic risk for schizophrenia
por: Hess, Jonathan L., et al.
Publicado: (2019)

Implementation of SCID Screening in Denmark
por: Bækvad-Hansen, Marie, et al.
Publicado: (2021)

FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses
por: Ahluwalia, Tarunveer S., et al.
Publicado: (2020)

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores
por: Albiñana, Clara, et al.
Publicado: (2023)

Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders
por: Nudel, Ron, et al.
Publicado: (2019)

Correction: Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorder
por: Nudel, Ron, et al.
Publicado: (2020)

High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA
por: Poulsen, Jesper Buchhave, et al.
Publicado: (2016)

Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders
por: Munk-Olsen, Trine, et al.
Publicado: (2023)

The Duffy-null genotype and risk of infection
por: Legge, Sophie E, et al.
Publicado: (2020)

Pharmacogenetics and adhd treatment outcomes in the danish population-based IPSYCH sample
por: Lunenburg, C., et al.
Publicado: (2021)

Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective
por: Nudel, Ron, et al.
Publicado: (2022)

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder
por: Martin, Joanna, et al.
Publicado: (2018)

Genome-wide scans using archived neonatal dried blood spot samples
por: Hollegaard, Mads V, et al.
Publicado: (2009)

Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci
por: Børglum, A D, et al.
Publicado: (2014)

Exploring Cuba’s population structure and demographic history using genome-wide data
por: Fortes-Lima, Cesar, et al.
Publicado: (2018)

Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia
por: Horsdal, Henriette Thisted, et al.
Publicado: (2019)

Robustness of genome-wide scanning using archived dried blood spot samples as a DNA source
por: Hollegaard, Mads V, et al.
Publicado: (2011)

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties
por: St Pourcain, B, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_91tf12ujcn5i0ojubgsftte130