Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China

We identified the genome sequences of two Mycobacterium tuberculosis isolates. They were resistant to rifampin and isoniazid, as determined by the agar proportion method, but were susceptible to isoniazid, as determined by the DNA array method. The genome sequences showed that a katG deletion led to...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Zhenghong, Ou, Weizheng, Fan, Xiangyu, Cui, Guzhen, Wang, Qiong, Li, Qiang, Sun, Rong, Wu, Xiaojuan, Qin, Wan, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754478/
https://www.ncbi.nlm.nih.gov/pubmed/29301898
http://dx.doi.org/10.1128/genomeA.01257-17
_version_ 1783290423159029760
author Chen, Zhenghong
Ou, Weizheng
Fan, Xiangyu
Cui, Guzhen
Wang, Qiong
Li, Qiang
Sun, Rong
Wu, Xiaojuan
Qin, Wan
Wang, Yan
author_facet Chen, Zhenghong
Ou, Weizheng
Fan, Xiangyu
Cui, Guzhen
Wang, Qiong
Li, Qiang
Sun, Rong
Wu, Xiaojuan
Qin, Wan
Wang, Yan
author_sort Chen, Zhenghong
collection PubMed
description We identified the genome sequences of two Mycobacterium tuberculosis isolates. They were resistant to rifampin and isoniazid, as determined by the agar proportion method, but were susceptible to isoniazid, as determined by the DNA array method. The genome sequences showed that a katG deletion led to the false diagnosis of isoniazid resistance by DNA array.
format Online
Article
Text
id pubmed-5754478
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher American Society for Microbiology
record_format MEDLINE/PubMed
spelling pubmed-57544782018-01-09 Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China Chen, Zhenghong Ou, Weizheng Fan, Xiangyu Cui, Guzhen Wang, Qiong Li, Qiang Sun, Rong Wu, Xiaojuan Qin, Wan Wang, Yan Genome Announc Prokaryotes We identified the genome sequences of two Mycobacterium tuberculosis isolates. They were resistant to rifampin and isoniazid, as determined by the agar proportion method, but were susceptible to isoniazid, as determined by the DNA array method. The genome sequences showed that a katG deletion led to the false diagnosis of isoniazid resistance by DNA array. American Society for Microbiology 2018-01-04 /pmc/articles/PMC5754478/ /pubmed/29301898 http://dx.doi.org/10.1128/genomeA.01257-17 Text en Copyright © 2018 Chen et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Prokaryotes
Chen, Zhenghong
Ou, Weizheng
Fan, Xiangyu
Cui, Guzhen
Wang, Qiong
Li, Qiang
Sun, Rong
Wu, Xiaojuan
Qin, Wan
Wang, Yan
Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China
title Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China
title_full Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China
title_fullStr Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China
title_full_unstemmed Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China
title_short Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China
title_sort complete genome sequences of two multidrug-resistant mycobacterium tuberculosis strains isolated in guiyang, china
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754478/
https://www.ncbi.nlm.nih.gov/pubmed/29301898
http://dx.doi.org/10.1128/genomeA.01257-17
work_keys_str_mv AT chenzhenghong completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT ouweizheng completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT fanxiangyu completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT cuiguzhen completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT wangqiong completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT liqiang completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT sunrong completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT wuxiaojuan completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT qinwan completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina
AT wangyan completegenomesequencesoftwomultidrugresistantmycobacteriumtuberculosisstrainsisolatedinguiyangchina

Ejemplares similares