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Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor

PURPOSE: To evaluate the rate of pyuria and bacteriuria after transurethral resection of bladder tumor (TURBT). MATERIALS AND METHODS: We retrospectively evaluated data obtained from 363 patients who underwent TURBT between October 2012 and December 2013 at Seoul National University Hospital. Urinal...

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Autores principales: Kim, Byung Soo, Tae, Bum Sik, Ku, Ja Hyeon, Kwak, Cheol, Kim, Hyeon Hoe, Jeong, Chang Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Urological Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754576/
https://www.ncbi.nlm.nih.gov/pubmed/29333509
http://dx.doi.org/10.4111/icu.2018.59.1.10
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author Kim, Byung Soo
Tae, Bum Sik
Ku, Ja Hyeon
Kwak, Cheol
Kim, Hyeon Hoe
Jeong, Chang Wook
author_facet Kim, Byung Soo
Tae, Bum Sik
Ku, Ja Hyeon
Kwak, Cheol
Kim, Hyeon Hoe
Jeong, Chang Wook
author_sort Kim, Byung Soo
collection PubMed
description PURPOSE: To evaluate the rate of pyuria and bacteriuria after transurethral resection of bladder tumor (TURBT). MATERIALS AND METHODS: We retrospectively evaluated data obtained from 363 patients who underwent TURBT between October 2012 and December 2013 at Seoul National University Hospital. Urinalysis and urine culture were assessed at 3, 6, 12, and 24 months postoperatively. Primary endpoint was the rate of bacteriuria (≥10(5)/mL in a midstream) and pyuria (white blood cells ≥5/high-power field). RESULTS: We analyzed 306 patients who were eligible for the study. Pyuria was present in 23.5% of patients in the 3rd postoperative month and in 31.7% of patients in the 24th postoperative month. Bacteriuria was present in 1.3% of patients in the 3rd postoperative month and in 2.6% of patients in the 24th postoperative month. Among urothelial carcinoma patients (n=220), 24.1% showed pyuria and 1.8% showed bacteriuria at the 3rd postoperative month. We found that 31.8% showed pyuria and 3.2% showed bacteriuria at the 24th postoperative month. There was no significant difference in the rate of pyuria and bacteriuria between the intravesical treatment group and the no-treatment group. Multivariate analysis demonstrated that pyuria in the 3rd postoperative month (odd ratio [OR], 2.254; p=0.039), tumor multiplicity (OR, 3.331; p=0.001), and the absence of intravesical treatment (OR, 4.927; p=0.001) increases the risk of tumor recurrence. CONCLUSIONS: A significant proportion of patients showed pyuria after TURBT during the follow-up period. Additionally, presence of pyuria in the short-term follow-up period after TURBT constitutes a risk factor for recurrence of bladder cancer.
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spelling pubmed-57545762018-01-12 Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor Kim, Byung Soo Tae, Bum Sik Ku, Ja Hyeon Kwak, Cheol Kim, Hyeon Hoe Jeong, Chang Wook Investig Clin Urol Original Article PURPOSE: To evaluate the rate of pyuria and bacteriuria after transurethral resection of bladder tumor (TURBT). MATERIALS AND METHODS: We retrospectively evaluated data obtained from 363 patients who underwent TURBT between October 2012 and December 2013 at Seoul National University Hospital. Urinalysis and urine culture were assessed at 3, 6, 12, and 24 months postoperatively. Primary endpoint was the rate of bacteriuria (≥10(5)/mL in a midstream) and pyuria (white blood cells ≥5/high-power field). RESULTS: We analyzed 306 patients who were eligible for the study. Pyuria was present in 23.5% of patients in the 3rd postoperative month and in 31.7% of patients in the 24th postoperative month. Bacteriuria was present in 1.3% of patients in the 3rd postoperative month and in 2.6% of patients in the 24th postoperative month. Among urothelial carcinoma patients (n=220), 24.1% showed pyuria and 1.8% showed bacteriuria at the 3rd postoperative month. We found that 31.8% showed pyuria and 3.2% showed bacteriuria at the 24th postoperative month. There was no significant difference in the rate of pyuria and bacteriuria between the intravesical treatment group and the no-treatment group. Multivariate analysis demonstrated that pyuria in the 3rd postoperative month (odd ratio [OR], 2.254; p=0.039), tumor multiplicity (OR, 3.331; p=0.001), and the absence of intravesical treatment (OR, 4.927; p=0.001) increases the risk of tumor recurrence. CONCLUSIONS: A significant proportion of patients showed pyuria after TURBT during the follow-up period. Additionally, presence of pyuria in the short-term follow-up period after TURBT constitutes a risk factor for recurrence of bladder cancer. The Korean Urological Association 2018-01 2017-12-15 /pmc/articles/PMC5754576/ /pubmed/29333509 http://dx.doi.org/10.4111/icu.2018.59.1.10 Text en © The Korean Urological Association, 2018 http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Byung Soo
Tae, Bum Sik
Ku, Ja Hyeon
Kwak, Cheol
Kim, Hyeon Hoe
Jeong, Chang Wook
Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor
title Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor
title_full Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor
title_fullStr Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor
title_full_unstemmed Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor
title_short Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor
title_sort rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754576/
https://www.ncbi.nlm.nih.gov/pubmed/29333509
http://dx.doi.org/10.4111/icu.2018.59.1.10
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