Cargando…
Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor
PURPOSE: To evaluate the rate of pyuria and bacteriuria after transurethral resection of bladder tumor (TURBT). MATERIALS AND METHODS: We retrospectively evaluated data obtained from 363 patients who underwent TURBT between October 2012 and December 2013 at Seoul National University Hospital. Urinal...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Urological Association
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754576/ https://www.ncbi.nlm.nih.gov/pubmed/29333509 http://dx.doi.org/10.4111/icu.2018.59.1.10 |
_version_ | 1783290445461192704 |
---|---|
author | Kim, Byung Soo Tae, Bum Sik Ku, Ja Hyeon Kwak, Cheol Kim, Hyeon Hoe Jeong, Chang Wook |
author_facet | Kim, Byung Soo Tae, Bum Sik Ku, Ja Hyeon Kwak, Cheol Kim, Hyeon Hoe Jeong, Chang Wook |
author_sort | Kim, Byung Soo |
collection | PubMed |
description | PURPOSE: To evaluate the rate of pyuria and bacteriuria after transurethral resection of bladder tumor (TURBT). MATERIALS AND METHODS: We retrospectively evaluated data obtained from 363 patients who underwent TURBT between October 2012 and December 2013 at Seoul National University Hospital. Urinalysis and urine culture were assessed at 3, 6, 12, and 24 months postoperatively. Primary endpoint was the rate of bacteriuria (≥10(5)/mL in a midstream) and pyuria (white blood cells ≥5/high-power field). RESULTS: We analyzed 306 patients who were eligible for the study. Pyuria was present in 23.5% of patients in the 3rd postoperative month and in 31.7% of patients in the 24th postoperative month. Bacteriuria was present in 1.3% of patients in the 3rd postoperative month and in 2.6% of patients in the 24th postoperative month. Among urothelial carcinoma patients (n=220), 24.1% showed pyuria and 1.8% showed bacteriuria at the 3rd postoperative month. We found that 31.8% showed pyuria and 3.2% showed bacteriuria at the 24th postoperative month. There was no significant difference in the rate of pyuria and bacteriuria between the intravesical treatment group and the no-treatment group. Multivariate analysis demonstrated that pyuria in the 3rd postoperative month (odd ratio [OR], 2.254; p=0.039), tumor multiplicity (OR, 3.331; p=0.001), and the absence of intravesical treatment (OR, 4.927; p=0.001) increases the risk of tumor recurrence. CONCLUSIONS: A significant proportion of patients showed pyuria after TURBT during the follow-up period. Additionally, presence of pyuria in the short-term follow-up period after TURBT constitutes a risk factor for recurrence of bladder cancer. |
format | Online Article Text |
id | pubmed-5754576 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Korean Urological Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-57545762018-01-12 Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor Kim, Byung Soo Tae, Bum Sik Ku, Ja Hyeon Kwak, Cheol Kim, Hyeon Hoe Jeong, Chang Wook Investig Clin Urol Original Article PURPOSE: To evaluate the rate of pyuria and bacteriuria after transurethral resection of bladder tumor (TURBT). MATERIALS AND METHODS: We retrospectively evaluated data obtained from 363 patients who underwent TURBT between October 2012 and December 2013 at Seoul National University Hospital. Urinalysis and urine culture were assessed at 3, 6, 12, and 24 months postoperatively. Primary endpoint was the rate of bacteriuria (≥10(5)/mL in a midstream) and pyuria (white blood cells ≥5/high-power field). RESULTS: We analyzed 306 patients who were eligible for the study. Pyuria was present in 23.5% of patients in the 3rd postoperative month and in 31.7% of patients in the 24th postoperative month. Bacteriuria was present in 1.3% of patients in the 3rd postoperative month and in 2.6% of patients in the 24th postoperative month. Among urothelial carcinoma patients (n=220), 24.1% showed pyuria and 1.8% showed bacteriuria at the 3rd postoperative month. We found that 31.8% showed pyuria and 3.2% showed bacteriuria at the 24th postoperative month. There was no significant difference in the rate of pyuria and bacteriuria between the intravesical treatment group and the no-treatment group. Multivariate analysis demonstrated that pyuria in the 3rd postoperative month (odd ratio [OR], 2.254; p=0.039), tumor multiplicity (OR, 3.331; p=0.001), and the absence of intravesical treatment (OR, 4.927; p=0.001) increases the risk of tumor recurrence. CONCLUSIONS: A significant proportion of patients showed pyuria after TURBT during the follow-up period. Additionally, presence of pyuria in the short-term follow-up period after TURBT constitutes a risk factor for recurrence of bladder cancer. The Korean Urological Association 2018-01 2017-12-15 /pmc/articles/PMC5754576/ /pubmed/29333509 http://dx.doi.org/10.4111/icu.2018.59.1.10 Text en © The Korean Urological Association, 2018 http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Byung Soo Tae, Bum Sik Ku, Ja Hyeon Kwak, Cheol Kim, Hyeon Hoe Jeong, Chang Wook Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor |
title | Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor |
title_full | Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor |
title_fullStr | Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor |
title_full_unstemmed | Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor |
title_short | Rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor |
title_sort | rate and association of lower urinary tract infection with recurrence after transurethral resection of bladder tumor |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754576/ https://www.ncbi.nlm.nih.gov/pubmed/29333509 http://dx.doi.org/10.4111/icu.2018.59.1.10 |
work_keys_str_mv | AT kimbyungsoo rateandassociationoflowerurinarytractinfectionwithrecurrenceaftertransurethralresectionofbladdertumor AT taebumsik rateandassociationoflowerurinarytractinfectionwithrecurrenceaftertransurethralresectionofbladdertumor AT kujahyeon rateandassociationoflowerurinarytractinfectionwithrecurrenceaftertransurethralresectionofbladdertumor AT kwakcheol rateandassociationoflowerurinarytractinfectionwithrecurrenceaftertransurethralresectionofbladdertumor AT kimhyeonhoe rateandassociationoflowerurinarytractinfectionwithrecurrenceaftertransurethralresectionofbladdertumor AT jeongchangwook rateandassociationoflowerurinarytractinfectionwithrecurrenceaftertransurethralresectionofbladdertumor |