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Does this treatment work for me? The patient’s role in assessing medical care

Randomised clinical trials are designed to determine whether a particular treatment is appropriate to make a significant difference to the health of a defined population and to aid its approval for use. For an accurate, cheap and simple assessment to see if a treatment benefits an individual person,...

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Detalles Bibliográficos
Autores principales: Neuhauser, Duncan V, Chu, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754871/
https://www.ncbi.nlm.nih.gov/pubmed/29445516
http://dx.doi.org/10.1136/bmjinnov-2016-000177
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author Neuhauser, Duncan V
Chu, Jennifer
author_facet Neuhauser, Duncan V
Chu, Jennifer
author_sort Neuhauser, Duncan V
collection PubMed
description Randomised clinical trials are designed to determine whether a particular treatment is appropriate to make a significant difference to the health of a defined population and to aid its approval for use. For an accurate, cheap and simple assessment to see if a treatment benefits an individual person, all that is needed is a pen, paper, simple pocket calculator and daily recording of a few variables. It requires the ability to read and write and to understand addition and division. Factorial design of experiments is used to show the impact of several variables and their interaction on the person’s health status. An example of a 75-year-old man with an enlarged prostate is used here to illustrate this approach. This person was able to understand and reduce side effects, lower the costs of medication by 83% and improve measured health status by 28%. A multivariate model for this person was then created with about 450 person-days of data.
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spelling pubmed-57548712018-02-12 Does this treatment work for me? The patient’s role in assessing medical care Neuhauser, Duncan V Chu, Jennifer BMJ Innov Diagnostics Randomised clinical trials are designed to determine whether a particular treatment is appropriate to make a significant difference to the health of a defined population and to aid its approval for use. For an accurate, cheap and simple assessment to see if a treatment benefits an individual person, all that is needed is a pen, paper, simple pocket calculator and daily recording of a few variables. It requires the ability to read and write and to understand addition and division. Factorial design of experiments is used to show the impact of several variables and their interaction on the person’s health status. An example of a 75-year-old man with an enlarged prostate is used here to illustrate this approach. This person was able to understand and reduce side effects, lower the costs of medication by 83% and improve measured health status by 28%. A multivariate model for this person was then created with about 450 person-days of data. BMJ Publishing Group 2017-07 2017-09-16 /pmc/articles/PMC5754871/ /pubmed/29445516 http://dx.doi.org/10.1136/bmjinnov-2016-000177 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Diagnostics
Neuhauser, Duncan V
Chu, Jennifer
Does this treatment work for me? The patient’s role in assessing medical care
title Does this treatment work for me? The patient’s role in assessing medical care
title_full Does this treatment work for me? The patient’s role in assessing medical care
title_fullStr Does this treatment work for me? The patient’s role in assessing medical care
title_full_unstemmed Does this treatment work for me? The patient’s role in assessing medical care
title_short Does this treatment work for me? The patient’s role in assessing medical care
title_sort does this treatment work for me? the patient’s role in assessing medical care
topic Diagnostics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754871/
https://www.ncbi.nlm.nih.gov/pubmed/29445516
http://dx.doi.org/10.1136/bmjinnov-2016-000177
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