Cargando…
HNF-4α promotes multidrug resistance of gastric cancer cells through the modulation of cell apoptosis
Multidrug resistance (MDR) typically leads to treatment failure, and is associated with disease progression of gastric cancer (GC). In the present study, a total of 15 aberrantly activated transcription factors (TFs) were detected in chemo-resistant GC cells using a TF Activation Profiling Plate Arr...
Autores principales: | Ma, Yubo, Wei, Xufu, Wu, Zhongjun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754880/ https://www.ncbi.nlm.nih.gov/pubmed/29344114 http://dx.doi.org/10.3892/ol.2017.7095 |
Ejemplares similares
-
Crystallization of hepatocyte nuclear factor 4α (HNF4α) in complex with the HNF1α promoter element
por: Lu, Peng, et al.
Publicado: (2008) -
Improved conditional expression systems resulting in physiological level of HNF4α expression confirm HNF4α induced apoptosis in the pancreatic β-cell line INS-1
por: Senkel, Sabine, et al.
Publicado: (2009) -
Liver fat storage is controlled by HNF4α through induction of lipophagy and is reversed by a potent HNF4α agonist
por: Lee, Seung-Hee, et al.
Publicado: (2021) -
Disruption of Tumor Suppressors HNF4α/HNF1α Causes Tumorigenesis in Liver
por: Teeli, Aamir Salam, et al.
Publicado: (2021) -
LncRNA Hnf4αos exacerbates liver ischemia/reperfusion injury in mice via Hnf4αos/Hnf4α duplex-mediated PGC1α suppression
por: Wang, Chaoqun, et al.
Publicado: (2022)