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Back to the future: new target-validated Rab antibodies for evaluating LRRK2 signalling in cell biology and Parkinson's disease
The addition of phosphate groups to substrates allows protein kinases to regulate a myriad of biological processes, and contextual analysis of protein-bound phosphate is important for understanding how kinases contribute to physiology and disease. Leucine-rich repeat kinase 2 (LRRK2) is a Ser/Thr ki...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Portland Press Ltd.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754967/ https://www.ncbi.nlm.nih.gov/pubmed/29305429 http://dx.doi.org/10.1042/BCJ20170870 |