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Metformin enhances the chemosensitivity of hepatocarcinoma cells to cisplatin through AMPK pathway

This study investigated the effect of metformin on chemosensitivity of hepatocarcinoma cells to cisplatin and the possible mechanism. HepG2 and Huh-7 hepatoma cells were treated with cisplatin at concentrations of 0, 2, 4, 6, 8 and 10 µM for 48 h. Proliferation of HepG2 and Huh-7 hepatoma cells were...

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Detalles Bibliográficos
Autores principales:	Dong, Hao, Huang, Jungang, Zheng, Kang, Tan, Dong, Chang, Qi, Gong, Genqiang, Zhang, Qing, Tang, Hanqiu, Sun, Jianguo, Zhang, Shaoyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755027/ https://www.ncbi.nlm.nih.gov/pubmed/29344225 http://dx.doi.org/10.3892/ol.2017.7198

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