In vivo and in vitro induction of the apoptotic effects of oxysophoridine on colorectal cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway

Oxysophoridine (OSR) is a major active alkaloid extracted from Sophoraalopecuroides L. The aim of the present study was to investigate the induction of the apoptotic effects of OSR on colorectal cancer cells in vivo and in vitro. The results of the MTT and colony formation assays demonstrated that t...

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Detalles Bibliográficos
Autores principales: Jin, Shao-Ju, Yang, Yun, Ma, Lei, Ma, Ben-Hui, Ren, Li-Ping, Guo, Liu-Cheng, Wang, Wen-Bao, Zhang, Yan-Xin, Zhao, Zhi-Jun, Cui, Mingchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755128/
https://www.ncbi.nlm.nih.gov/pubmed/29344242
http://dx.doi.org/10.3892/ol.2017.7227

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