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Inhibition of neddylation facilitates cell migration through enhanced phosphorylation of caveolin-1 in PC3 and U373MG cells

BACKGROUND: Protein neddylation is a post-translational modification by a covalent conjugation with the neural precursor cell expressed, developmentally downregulated 8 (NEDD8). Although this process has been reported to participate in diverse cellular signaling, little is known about its role in ca...

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Detalles Bibliográficos
Autores principales: Park, Sung Yeon, Park, Jong-Wan, Lee, Gun-Woo, Li, Lan, Chun, Yang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755266/
https://www.ncbi.nlm.nih.gov/pubmed/29301501
http://dx.doi.org/10.1186/s12885-017-3942-9