Cargando…

Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification

Calcific aortic valve disease (CAVD) is characterized by the progressive thickening of the aortic valve leaflets. It is a condition frequently found in the elderly and end-stage renal disease (ESRD) patients, who commonly suffer from hyperphosphatemia and hypercalcemia. At present, there are no medi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Cui, Zhu, Dongxing, Markby, Greg, Corcoran, Brendan M., Farquharson, Colin, Macrae, Vicky E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2017
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755457/ https://www.ncbi.nlm.nih.gov/pubmed/29286439 http://dx.doi.org/10.3791/56126

Ejemplares similares

Exploiting novel valve interstitial cell lines to study calcific aortic valve disease
por: Tsang, Hiu-Gwen, et al.
Publicado: (2018)

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk
por: Zhou, Qian, et al.
Publicado: (2021)

End stage renal disease‐induced hypercalcemia may promote aortic valve calcification via Annexin VI enrichment of valve interstitial cell derived‐matrix vesicles
por: Cui, Lin, et al.
Publicado: (2017)

Comparative Transcriptomic Profiling and Gene Expression for Myxomatous Mitral Valve Disease in the Dog and Human
por: Markby, Greg R., et al.
Publicado: (2017)

Disease Severity-Associated Gene Expression in Canine Myxomatous Mitral Valve Disease Is Dominated by TGFβ Signaling
por: Markby, Greg R., et al.
Publicado: (2020)

Lipoprotein(a), a Lethal Player in Calcific Aortic Valve Disease
por: Hu, Jiahui, et al.
Publicado: (2022)

Evaluation of canine 2D cell cultures as models of myxomatous mitral valve degeneration
por: Tan, Karen, et al.
Publicado: (2019)

Isolation and culture of rat aortic valve interstitial cells
por: Chen, Huiqiang, et al.
Publicado: (2016)

Biomarkers Associated With Aortic Valve Calcification: Should We Focus on Sex Specific Processes?
por: Peeters, Frederique E. C. M., et al.
Publicado: (2020)

Mechanisms and Clinical Consequences of Vascular Calcification
por: Zhu, Dongxing, et al.
Publicado: (2012)

TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve disease
por: McNair, Andrew J., et al.
Publicado: (2023)

A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice
por: Eley, Lorriane, et al.
Publicado: (2018)

Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
por: Houston, Dean A., et al.
Publicado: (2016)

PALMD regulates aortic valve calcification via altered glycolysis and NF-κB–mediated inflammation
por: Wang, Siying, et al.
Publicado: (2022)

Purinergic Signaling in Pathologic Osteogenic Differentiation of Aortic Valve Interstitial Cells from Patients with Aortic Valve Calcification
por: Klauzen, Polina, et al.
Publicado: (2023)

Functional differences in human aortic valve interstitial cells from patients with varying calcific aortic valve disease
por: Tuscher, Robin, et al.
Publicado: (2023)

Decreased Glucagon-Like Peptide-1 Is Associated With Calcific Aortic Valve Disease: GLP-1 Suppresses the Calcification of Aortic Valve Interstitial Cells
por: Xiao, Fan, et al.
Publicado: (2021)

TGF‐β‐induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease
por: Tang, Qiyu, et al.
Publicado: (2023)

Lipoprotein(a) Induces Human Aortic Valve Interstitial Cell Calcification
por: Yu, Bin, et al.
Publicado: (2017)

Telomere Length in Valve Tissue Is Shorter in Individuals With Aortic Stenosis and in Calcified Valve Areas
por: Saraieva, Ilona, et al.
Publicado: (2021)

Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3
por: The, Erlinda, et al.
Publicado: (2022)

Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification
por: Rutkovskiy, Arkady, et al.
Publicado: (2017)

Mitochondrial Dysfunction: Cause or Consequence of Vascular Calcification?
por: Phadwal, Kanchan, et al.
Publicado: (2021)

NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease
por: Wang, Yidong, et al.
Publicado: (2021)

The Appearance and Modulation of Osteocyte Marker Expression during Calcification of Vascular Smooth Muscle Cells
por: Zhu, Dongxing, et al.
Publicado: (2011)

Radiation Induces Valvular Interstitial Cell Calcific Response in an in vitro Model of Calcific Aortic Valve Disease
por: Meerman, Manon, et al.
Publicado: (2021)

Comparative transcriptomic profiling of myxomatous mitral valve disease in the cavalier King Charles spaniel
por: Markby, G. R., et al.
Publicado: (2020)

Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease
por: Sikura, Katalin Éva, et al.
Publicado: (2019)

Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells
por: Carracedo, Miguel, et al.
Publicado: (2019)

Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity
por: Iqbal, Farwah, et al.
Publicado: (2023)

Semicarbazide-Sensitive Amine Oxidase Increases in Calcific Aortic Valve Stenosis and Contributes to Valvular Interstitial Cell Calcification
por: Mercier, Nathalie, et al.
Publicado: (2020)

The Role of Wnt/β-Catenin Pathway Mediators in Aortic Valve Stenosis
por: Khan, Kashif, et al.
Publicado: (2020)

Crenigacestat (LY3039478) inhibits osteogenic differentiation of human valve interstitial cells from patients with aortic valve calcification in vitro
por: Lobov, Arseniy A., et al.
Publicado: (2022)

Sex-specific aortic valve calcifications in patients undergoing transcatheter aortic valve implantation
por: Hokken, Thijmen W, et al.
Publicado: (2023)

Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification
por: Rodriguez, Karien J, et al.
Publicado: (2014)

Extensive calcification of the mitral valve annulus in transcatheter aortic valve implants
por: Haensig, Martin, et al.
Publicado: (2021)

Expression of Calcification and Extracellular Matrix Genes in the Cardiovascular System of the Healthy Domestic Sheep (Ovis aries)
por: Tsang, Hiu-Gwen, et al.
Publicado: (2020)

Proteoglycan 4 is Increased in Human Calcified Aortic Valves and Enhances Valvular Interstitial Cell Calcification
por: Artiach, Gonzalo, et al.
Publicado: (2020)

The Natural Product Andrographolide Ameliorates Calcific Aortic Valve Disease by Regulating the Proliferation of Valve Interstitial Cells via the MAPK-ERK Pathway
por: Huang, Yuming, et al.
Publicado: (2022)

Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease
por: Huang, Yuming, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5dcgttsrvnrkm57510he5fi345