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Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Proteins interact with their ligands to form active and dynamic assemblies which carry out various cellular functions. Elucidating these interactions is therefore fundamental for the understanding of cellular processes. However, many protein complexes are dynamic assemblies and are not accessible by...

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Detalles Bibliográficos
Autores principales:	Haupt, Caroline, Hofmann, Tommy, Wittig, Sabine, Kostmann, Susann, Politis, Argyris, Schmidt, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2017
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755487/ https://www.ncbi.nlm.nih.gov/pubmed/29286378 http://dx.doi.org/10.3791/56747

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