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Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis

Small intestinal tumors are rare with adenocarcinoma of the small intestine accounting for less than 2% of all gastrointestinal cancers. Primary jejunal adenocarcinoma constitutes a minute portion of small intestine adenocarcinomas. Clinically, this cancer presents at latter stages of its progressio...

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Autores principales: Ofori, Emmanuel, Ramai, Daryl, Papafragkakis, Charilaos, Changela, Kinesh, Krishnaiah, Mahesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755639/
https://www.ncbi.nlm.nih.gov/pubmed/29317945
http://dx.doi.org/10.14740/gr879w
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author Ofori, Emmanuel
Ramai, Daryl
Papafragkakis, Charilaos
Changela, Kinesh
Krishnaiah, Mahesh
author_facet Ofori, Emmanuel
Ramai, Daryl
Papafragkakis, Charilaos
Changela, Kinesh
Krishnaiah, Mahesh
author_sort Ofori, Emmanuel
collection PubMed
description Small intestinal tumors are rare with adenocarcinoma of the small intestine accounting for less than 2% of all gastrointestinal cancers. Primary jejunal adenocarcinoma constitutes a minute portion of small intestine adenocarcinomas. Clinically, this cancer presents at latter stages of its progression, mainly due to vague and non-specific symptoms, and the difficulty encountered in accessing the jejunum on upper endoscopy. Diagnosis of jejunal adenocarcinoma is usually inconclusive with the use of computed tomography (CT) scan, small bowel series, or upper endoscopy. Laparoscopy followed by frozen section biopsy provides a definitive diagnosis. In the past decade, balloon-assisted enteroscopy (BAE) and capsule endoscopy have become popular as useful modalities for diagnosing small bowel diseases. Wide excisional jejunectomy is the only treatment option with an estimated 5-year survival of 40-65%. Physicians are advised to suspect jejunal adenocarcinoma as a differential diagnosis in patients who present with non-specific symptoms of abdominal pain, nausea, vomiting, weight loss, anemia, gastrointestinal bleeding or signs of small bowel obstruction. We present a rare case of a 37-year-old woman with suspected bilateral ovarian masses, which was immunohistochemically confirmed as primary jejunal adenocarcinoma with bilateral ovarian metastasis.
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spelling pubmed-57556392018-01-09 Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis Ofori, Emmanuel Ramai, Daryl Papafragkakis, Charilaos Changela, Kinesh Krishnaiah, Mahesh Gastroenterology Res Case Report Small intestinal tumors are rare with adenocarcinoma of the small intestine accounting for less than 2% of all gastrointestinal cancers. Primary jejunal adenocarcinoma constitutes a minute portion of small intestine adenocarcinomas. Clinically, this cancer presents at latter stages of its progression, mainly due to vague and non-specific symptoms, and the difficulty encountered in accessing the jejunum on upper endoscopy. Diagnosis of jejunal adenocarcinoma is usually inconclusive with the use of computed tomography (CT) scan, small bowel series, or upper endoscopy. Laparoscopy followed by frozen section biopsy provides a definitive diagnosis. In the past decade, balloon-assisted enteroscopy (BAE) and capsule endoscopy have become popular as useful modalities for diagnosing small bowel diseases. Wide excisional jejunectomy is the only treatment option with an estimated 5-year survival of 40-65%. Physicians are advised to suspect jejunal adenocarcinoma as a differential diagnosis in patients who present with non-specific symptoms of abdominal pain, nausea, vomiting, weight loss, anemia, gastrointestinal bleeding or signs of small bowel obstruction. We present a rare case of a 37-year-old woman with suspected bilateral ovarian masses, which was immunohistochemically confirmed as primary jejunal adenocarcinoma with bilateral ovarian metastasis. Elmer Press 2017-12 2018-01-03 /pmc/articles/PMC5755639/ /pubmed/29317945 http://dx.doi.org/10.14740/gr879w Text en Copyright 2017, Ofori et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ofori, Emmanuel
Ramai, Daryl
Papafragkakis, Charilaos
Changela, Kinesh
Krishnaiah, Mahesh
Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis
title Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis
title_full Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis
title_fullStr Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis
title_full_unstemmed Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis
title_short Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis
title_sort primary jejunal adenocarcinoma presenting as bilateral ovarian metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755639/
https://www.ncbi.nlm.nih.gov/pubmed/29317945
http://dx.doi.org/10.14740/gr879w
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