A clinically parameterized mathematical model of Shigella immunity to inform vaccine design

We refine and clinically parameterize a mathematical model of the humoral immune response against Shigella, a diarrheal bacteria that infects 80-165 million people and kills an estimated 600,000 people worldwide each year. Using Latin hypercube sampling and Monte Carlo simulations for parameter esti...

Descripción completa

Detalles Bibliográficos
Autores principales: Davis, Courtney L., Wahid, Rezwanul, Toapanta, Franklin R., Simon, Jakub K., Sztein, Marcelo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755796/
https://www.ncbi.nlm.nih.gov/pubmed/29304144
http://dx.doi.org/10.1371/journal.pone.0189571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755796/
https://www.ncbi.nlm.nih.gov/pubmed/29304144
http://dx.doi.org/10.1371/journal.pone.0189571

Ejemplares similares