Soluble guanylate cyclase stimulation reduces oxidative stress in experimental Chronic Obstructive Pulmonary Disease

OBJECTIVE: Soluble guanylate cyclase (sGC) is a key enzyme of the nitric oxide–cyclic guanosine 3′,5′-monophosphate (NO–cGMP) signaling pathway, and its pharmacological stimulation has been shown to prevent the development of emphysema and pulmonary vascular remodeling in animal models of chronic ob...

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Detalles Bibliográficos
Autores principales: Paul, Tanja, Salazar-Degracia, Anna, Peinado, Victor I., Tura-Ceide, Olga, Blanco, Isabel, Barreiro, Esther, Barberà, Joan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755849/
https://www.ncbi.nlm.nih.gov/pubmed/29304131
http://dx.doi.org/10.1371/journal.pone.0190628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755849/
https://www.ncbi.nlm.nih.gov/pubmed/29304131
http://dx.doi.org/10.1371/journal.pone.0190628

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