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β-cell-specific overexpression of adiponectin receptor 1 does not improve diabetes mellitus in Akita mice

Adiponectin, a metabolically-active cytokine secreted from adipose tissue, is reported to have anti-apoptotic effects on β-cells as well as anti-hyperglycemic effects through adiponectin receptor signaling. However, the anti-apoptotic effects of adiponectin on β-cells have not been confirmed in esta...

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Detalles Bibliográficos
Autores principales: Choi, Jungmi, Kobayashi, Hatasu, Okuda, Hiroko, Harada, Kouji H., Takeda, Midori, Fujimoto, Hiroyuki, Yamane, Shunsuke, Tanaka, Daisuke, Youssefian, Shohab, Inagaki, Nobuya, Koizumi, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755906/
https://www.ncbi.nlm.nih.gov/pubmed/29304075
http://dx.doi.org/10.1371/journal.pone.0190863