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Serine racemase deletion attenuates neurodegeneration and microvascular damage in diabetic retinopathy

Diabetic retinopathy (DR) is a leading cause of blindness. DR is recognized as a microvascular disease and inner retinal neurodegeneration. In the course of retinal neurodegeneration, N-methyl-D-aspartate receptor (NMDAR)-mediated excitotoxicity is involved. Full activation of NMDAR requires binding...

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Detalles Bibliográficos
Autores principales: Ozaki, Hironori, Inoue, Ran, Matsushima, Takako, Sasahara, Masakiyo, Hayashi, Atsushi, Mori, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755926/
https://www.ncbi.nlm.nih.gov/pubmed/29304076
http://dx.doi.org/10.1371/journal.pone.0190864