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Xanthohumol Protects Morphology and Function in a Mouse Model of Retinal Degeneration

PURPOSE: To investigate whether treatment with xanthohumol (XN), the principal prenylated chalconoid from Humulus lupulus (hops), is protective in a mouse model of light-induced retinal degeneration (LIRD). METHODS: Mice (129S2/SvPasCrl) were intraperitoneally injected with vehicle or XN prior to to...

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Detalles Bibliográficos
Autores principales: Henneman, Nathaniel F., Foster, Stephanie L., Chrenek, Micah A., Sellers, Jana T., Wright, Charles B., Schmidt, Robin H., Nickerson, John M., Boatright, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756043/
https://www.ncbi.nlm.nih.gov/pubmed/29305606
http://dx.doi.org/10.1167/iovs.17-22132