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Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content
Genomic location can inform on potential function and recruitment signals for chromatin-associated proteins. High mobility group (Hmg) proteins are of similar size as histones with Hmga1 and Hmga2 being particularly abundant in replicating normal tissues and in cancerous cells. While several roles f...
Autores principales: | Colombo, Daniele F, Burger, Lukas, Baubec, Tuncay, Schübeler, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756049/ https://www.ncbi.nlm.nih.gov/pubmed/29267285 http://dx.doi.org/10.1371/journal.pgen.1007102 |
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