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Clinical trial experience with CA4P anticancer therapy: focus on efficacy, cardiovascular adverse events, and hypertension management
Combretastatin A4-phosphate (CA4P) is a vascular-disrupting agent (VDA) in clinical development for the treatment of ovarian and other cancers. In contrast to antiangiogenic agents, such as bevacizumab, which suppress the development of new tumor vasculature, VDAs target established tumor vasculatur...
Autores principales: | Grisham, Rachel, Ky, Bonnie, Tewari, Krishnansu S., Chaplin, David J., Walker, Joan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756341/ https://www.ncbi.nlm.nih.gov/pubmed/29318022 http://dx.doi.org/10.1186/s40661-017-0058-5 |
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