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Development of the excitation-contraction coupling machinery and its relation to myofibrillogenesis in human iPSC-derived skeletal myocytes

BACKGROUND: Human induced pluripotent stem cells-derived myogenic progenitors develop functional and ultrastructural features typical of skeletal muscle when differentiated in culture. Besides disease-modeling, such a system can be used to clarify basic aspects of human skeletal muscle development....

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Detalles Bibliográficos
Autores principales: Lainé, Jeanne, Skoglund, Gunnar, Fournier, Emmanuel, Tabti, Nacira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756430/
https://www.ncbi.nlm.nih.gov/pubmed/29304851
http://dx.doi.org/10.1186/s13395-017-0147-5