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Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient

BACKGROUND & AIMS: We report a novel experimental immunotherapeutic approach in a patient with metastatic intrahepatic cholangiocarcinoma. In the 5 year course of the disease, the initial tumor mass, two local recurrences and a lung metastasis were surgically removed. Lacking alternative treatme...

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Detalles Bibliográficos
Autores principales: Löffler, Markus W., Chandran, P. Anoop, Laske, Karoline, Schroeder, Christopher, Bonzheim, Irina, Walzer, Mathias, Hilke, Franz J., Trautwein, Nico, Kowalewski, Daniel J., Schuster, Heiko, Günder, Marc, Carcamo Yañez, Viviana A., Mohr, Christopher, Sturm, Marc, Nguyen, Huu-Phuc, Riess, Olaf, Bauer, Peter, Nahnsen, Sven, Nadalin, Silvio, Zieker, Derek, Glatzle, Jörg, Thiel, Karolin, Schneiderhan-Marra, Nicole, Clasen, Stephan, Bösmüller, Hans, Fend, Falko, Kohlbacher, Oliver, Gouttefangeas, Cécile, Stevanović, Stefan, Königsrainer, Alfred, Rammensee, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756536/
https://www.ncbi.nlm.nih.gov/pubmed/27397612
http://dx.doi.org/10.1016/j.jhep.2016.06.027