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Activation of a chondrocyte volume-sensitive Cl(−) conductance prior to macroscopic cartilage lesion formation in the rabbit knee anterior cruciate ligament transection osteoarthritis model

OBJECTIVE: The anterior cruciate ligament transection (ACLT) rabbit osteoarthritis (OA) model confers permanent knee instability and induces joint degeneration. The degeneration process is complex, but includes chondrocyte apoptosis and OA-like loss of cartilage integrity. Previously, we reported th...

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Detalles Bibliográficos
Autores principales:	Kumagai, K., Toyoda, F., Staunton, C.A., Maeda, T., Okumura, N., Matsuura, H., Matsusue, Y., Imai, S., Barrett-Jolley, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	W.B. Saunders For The Osteoarthritis Research Society 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756537/ https://www.ncbi.nlm.nih.gov/pubmed/27266646 http://dx.doi.org/10.1016/j.joca.2016.05.019

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